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Orthogonal IMiD-Degron Pairs Induce Selective Protein Degradation in Cells.
Brennan PJ, Saunders RE, Spanou M, Serafini M, Sun L, Heger GP, Konopacka A, Beveridge RD, Gordon L, Bunally SB, Saudemont A, Benowitz AB, Martinez-Fleites C, Queisser MA, An H, Deane CM, Hann MM, Brayshaw LL, Conway SJ. Brennan PJ, et al. Among authors: hann mm. bioRxiv [Preprint]. 2024 Mar 16:2024.03.15.585309. doi: 10.1101/2024.03.15.585309. bioRxiv. 2024. PMID: 38559242 Free PMC article. Preprint.
The PROTACtable genome.
Schneider M, Radoux CJ, Hercules A, Ochoa D, Dunham I, Zalmas LP, Hessler G, Ruf S, Shanmugasundaram V, Hann MM, Thomas PJ, Queisser MA, Benowitz AB, Brown K, Leach AR. Schneider M, et al. Among authors: hann mm. Nat Rev Drug Discov. 2021 Oct;20(10):789-797. doi: 10.1038/s41573-021-00245-x. Epub 2021 Jul 20. Nat Rev Drug Discov. 2021. PMID: 34285415 Review.
A Photoaffinity-Based Fragment-Screening Platform for Efficient Identification of Protein Ligands.
Grant EK, Fallon DJ, Hann MM, Fantom KGM, Quinn C, Zappacosta F, Annan RS, Chung CW, Bamborough P, Dixon DP, Stacey P, House D, Patel VK, Tomkinson NCO, Bush JT. Grant EK, et al. Among authors: hann mm. Angew Chem Int Ed Engl. 2020 Nov 16;59(47):21096-21105. doi: 10.1002/anie.202008361. Epub 2020 Sep 7. Angew Chem Int Ed Engl. 2020. PMID: 32745361 Free article.
Approaches to target tractability assessment - a practical perspective.
Brown KK, Hann MM, Lakdawala AS, Santos R, Thomas PJ, Todd K. Brown KK, et al. Among authors: hann mm. Medchemcomm. 2018 Feb 14;9(4):606-613. doi: 10.1039/c7md00633k. eCollection 2018 Apr 1. Medchemcomm. 2018. PMID: 30108951 Free PMC article. Review.
34 results