Wells AD - Search Results

1

GWAS-informed data integration and non-coding CRISPRi screen illuminate genetic etiology of bone mineral density.

Conery M, Pippin JA, Wagley Y, Trang K, Pahl MC, Villani DA, Favazzo LJ, Ackert-Bicknell CL, Zuscik MJ, Katsevich E, Wells AD, Zemel BS, Voight BF, Hankenson KD, Chesi A, Grant SFA. Conery M, et al. Among authors: wells ad. bioRxiv [Preprint]. 2024 Mar 20:2024.03.19.585778. doi: 10.1101/2024.03.19.585778. bioRxiv. 2024. PMID: 38562830 Free PMC article. Preprint.

2

A ChIP-seq-defined genome-wide map of MEF2C binding reveals inflammatory pathways associated with its role in bone density determination.

Johnson ME, Deliard S, Zhu F, Xia Q, Wells AD, Hankenson KD, Grant SF. Johnson ME, et al. Among authors: wells ad. Calcif Tissue Int. 2014 Apr;94(4):396-402. doi: 10.1007/s00223-013-9824-5. Epub 2013 Dec 15. Calcif Tissue Int. 2014. PMID: 24337390

3

Genome-wide analyses of ChIP-Seq derived FOXA2 DNA occupancy in liver points to genetic networks underpinning multiple complex traits.

Johnson ME, Schug J, Wells AD, Kaestner KH, Grant SF. Johnson ME, et al. Among authors: wells ad. J Clin Endocrinol Metab. 2014 Aug;99(8):E1580-5. doi: 10.1210/jc.2013-4503. Epub 2014 May 30. J Clin Endocrinol Metab. 2014. PMID: 24878043 Free PMC article.

4

A Dementia-Associated Risk Variant near TMEM106B Alters Chromatin Architecture and Gene Expression.

Gallagher MD, Posavi M, Huang P, Unger TL, Berlyand Y, Gruenewald AL, Chesi A, Manduchi E, Wells AD, Grant SFA, Blobel GA, Brown CD, Chen-Plotkin AS. Gallagher MD, et al. Among authors: wells ad. Am J Hum Genet. 2017 Nov 2;101(5):643-663. doi: 10.1016/j.ajhg.2017.09.004. Epub 2017 Oct 19. Am J Hum Genet. 2017. PMID: 29056226 Free PMC article.

5

Leveraging epigenomics and contactomics data to investigate SNP pairs in GWAS.

Manduchi E, Williams SM, Chesi A, Johnson ME, Wells AD, Grant SFA, Moore JH. Manduchi E, et al. Among authors: wells ad. Hum Genet. 2018 May;137(5):413-425. doi: 10.1007/s00439-018-1893-0. Epub 2018 May 24. Hum Genet. 2018. PMID: 29797095 Free PMC article.

6

Genome-scale Capture C promoter interactions implicate effector genes at GWAS loci for bone mineral density.

Chesi A, Wagley Y, Johnson ME, Manduchi E, Su C, Lu S, Leonard ME, Hodge KM, Pippin JA, Hankenson KD, Wells AD, Grant SFA. Chesi A, et al. Among authors: wells ad. Nat Commun. 2019 Mar 19;10(1):1260. doi: 10.1038/s41467-019-09302-x. Nat Commun. 2019. PMID: 30890710 Free PMC article.

7

Canonical Notch signaling is required for bone morphogenetic protein-mediated human osteoblast differentiation.

Wagley Y, Chesi A, Acevedo PK, Lu S, Wells AD, Johnson ME, Grant SFA, Hankenson KD. Wagley Y, et al. Among authors: wells ad. Stem Cells. 2020 Oct 1;38(10):1332-1347. doi: 10.1002/stem.3245. Epub 2020 Jun 24. Stem Cells. 2020. PMID: 32535942 Free article.

8

Mapping effector genes at lupus GWAS loci using promoter Capture-C in follicular helper T cells.

Su C, Johnson ME, Torres A, Thomas RM, Manduchi E, Sharma P, Mehra P, Le Coz C, Leonard ME, Lu S, Hodge KM, Chesi A, Pippin J, Romberg N, Grant SFA, Wells AD. Su C, et al. Among authors: wells ad. Nat Commun. 2020 Jul 3;11(1):3294. doi: 10.1038/s41467-020-17089-5. Nat Commun. 2020. PMID: 32620744 Free PMC article.

9

Next steps in the identification of gene targets for type 1 diabetes.

Grant SFA, Wells AD, Rich SS. Grant SFA, et al. Among authors: wells ad. Diabetologia. 2020 Nov;63(11):2260-2269. doi: 10.1007/s00125-020-05248-8. Epub 2020 Aug 14. Diabetologia. 2020. PMID: 32797243 Free PMC article. Review.

10

Variant-to-Gene-Mapping Analyses Reveal a Role for the Hypothalamus in Genetic Susceptibility to Inflammatory Bowel Disease.

Lasconi C, Pahl MC, Cousminer DL, Doege CA, Chesi A, Hodge KM, Leonard ME, Lu S, Johnson ME, Su C, Hammond RK, Pippin JA, Terry NA, Ghanem LR, Leibel RL, Wells AD, Grant SFA. Lasconi C, et al. Among authors: wells ad. Cell Mol Gastroenterol Hepatol. 2021;11(3):667-682. doi: 10.1016/j.jcmgh.2020.10.004. Epub 2020 Oct 16. Cell Mol Gastroenterol Hepatol. 2021. PMID: 33069917 Free PMC article.

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