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Loss of an extensive ciliary connectome induces proteostasis and cell fate switching in a severe motile ciliopathy.
Brody SL, Pan J, Huang T, Xu J, Xu H, Koenitizer J, Brennan SK, Nanjundappa R, Saba TG, Berical A, Hawkins FJ, Wang X, Zhang R, Mahjoub MR, Horani A, Dutcher SK. Brody SL, et al. Among authors: hawkins fj. bioRxiv [Preprint]. 2024 Mar 21:2024.03.20.585965. doi: 10.1101/2024.03.20.585965. bioRxiv. 2024. PMID: 38562900 Free PMC article. Preprint.
Derivation of Airway Basal Stem Cells from Human Pluripotent Stem Cells.
Hawkins FJ, Suzuki S, Beermann ML, Barillà C, Wang R, Villacorta-Martin C, Berical A, Jean JC, Le Suer J, Matte T, Simone-Roach C, Tang Y, Schlaeger TM, Crane AM, Matthias N, Huang SXL, Randell SH, Wu J, Spence JR, Carraro G, Stripp BR, Rab A, Sorsher EJ, Horani A, Brody SL, Davis BR, Kotton DN. Hawkins FJ, et al. Cell Stem Cell. 2021 Jan 7;28(1):79-95.e8. doi: 10.1016/j.stem.2020.09.017. Epub 2020 Oct 23. Cell Stem Cell. 2021. PMID: 33098807 Free PMC article.
A multimodal iPSC platform for cystic fibrosis drug testing.
Berical A, Lee RE, Lu J, Beermann ML, Le Suer JA, Mithal A, Thomas D, Ranallo N, Peasley M, Stuffer A, Bukis K, Seymour R, Harrington J, Coote K, Valley H, Hurley K, McNally P, Mostoslavsky G, Mahoney J, Randell SH, Hawkins FJ. Berical A, et al. Among authors: hawkins fj. Nat Commun. 2022 Jul 29;13(1):4270. doi: 10.1038/s41467-022-31854-8. Nat Commun. 2022. PMID: 35906215 Free PMC article.
Airway stem cell reconstitution by the transplantation of primary or pluripotent stem cell-derived basal cells.
Ma L, Thapa BR, Le Suer JA, Tilston-Lünel A, Herriges MJ, Berical A, Beermann ML, Wang F, Bawa PS, Kohn A, Ysasi AB, Kiyokawa H, Matte TM, Randell SH, Varelas X, Hawkins FJ, Kotton DN. Ma L, et al. Among authors: hawkins fj. Cell Stem Cell. 2023 Sep 7;30(9):1199-1216.e7. doi: 10.1016/j.stem.2023.07.014. Epub 2023 Aug 24. Cell Stem Cell. 2023. PMID: 37625411 Free PMC article.
SARS-CoV-2 Infection of Pluripotent Stem Cell-derived Human Lung Alveolar Type 2 Cells Elicits a Rapid Epithelial-Intrinsic Inflammatory Response.
Huang J, Hume AJ, Abo KM, Werder RB, Villacorta-Martin C, Alysandratos KD, Beermann ML, Simone-Roach C, Lindstrom-Vautrin J, Olejnik J, Suder EL, Bullitt E, Hinds A, Sharma A, Bosmann M, Wang R, Hawkins F, Burks EJ, Saeed M, Wilson AA, Mühlberger E, Kotton DN. Huang J, et al. bioRxiv [Preprint]. 2020 Aug 6:2020.06.30.175695. doi: 10.1101/2020.06.30.175695. bioRxiv. 2020. PMID: 32637964 Free PMC article. Updated. Preprint.
Human iPSC-derived alveolar and airway epithelial cells can be cultured at air-liquid interface and express SARS-CoV-2 host factors.
Abo KM, Ma L, Matte T, Huang J, Alysandratos KD, Werder RB, Mithal A, Beermann ML, Lindstrom-Vautrin J, Mostoslavsky G, Ikonomou L, Kotton DN, Hawkins F, Wilson A, Villacorta-Martin C. Abo KM, et al. bioRxiv [Preprint]. 2020 Jun 4:2020.06.03.132639. doi: 10.1101/2020.06.03.132639. bioRxiv. 2020. PMID: 32577635 Free PMC article. Preprint.
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