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The β-Secretase BACE1 Drives Fibroblast Activation in Systemic Sclerosis through the APP/β-Catenin/Notch Signaling Axis.
Wasson CW, De Lorenzis E, Clavane EM, Ross RL, Walker KA, Caballero-Ruiz B, Antinozzi C, Wells R, Migneco G, Brown JMY, Turvey SJ, Simmons KJ, Riobo-Del Galdo NA, Di Luigi L, McKimmie CS, Del Galdo F, Meakin PJ. Wasson CW, et al. Among authors: ross rl. J Invest Dermatol. 2024 Apr 1:S0022-202X(24)00265-3. doi: 10.1016/j.jid.2024.03.024. Online ahead of print. J Invest Dermatol. 2024. PMID: 38570030 Free article.
Human papillomavirus type 18 E5 oncogene supports cell cycle progression and impairs epithelial differentiation by modulating growth factor receptor signalling during the virus life cycle.
Wasson CW, Morgan EL, Müller M, Ross RL, Hartley M, Roberts S, Macdonald A. Wasson CW, et al. Among authors: ross rl. Oncotarget. 2017 Oct 6;8(61):103581-103600. doi: 10.18632/oncotarget.21658. eCollection 2017 Nov 28. Oncotarget. 2017. PMID: 29262586 Free PMC article.
Metabolic control of BRISC-SHMT2 assembly regulates immune signalling.
Walden M, Tian L, Ross RL, Sykora UM, Byrne DP, Hesketh EL, Masandi SK, Cassel J, George R, Ault JR, El Oualid F, Pawłowski K, Salvino JM, Eyers PA, Ranson NA, Del Galdo F, Greenberg RA, Zeqiraj E. Walden M, et al. Among authors: ross rl. Nature. 2019 Jun;570(7760):194-199. doi: 10.1038/s41586-019-1232-1. Epub 2019 May 29. Nature. 2019. PMID: 31142841 Free PMC article.
Targeting human plasmacytoid dendritic cells through BDCA2 prevents skin inflammation and fibrosis in a novel xenotransplant mouse model of scleroderma.
Ross RL, Corinaldesi C, Migneco G, Carr IM, Antanaviciute A, Wasson CW, Carriero A, Distler JHW, Holmes S, El-Sherbiny YM, McKimmie CS, Del Galdo F. Ross RL, et al. Ann Rheum Dis. 2021 Jul;80(7):920-929. doi: 10.1136/annrheumdis-2020-218439. Epub 2021 Feb 4. Ann Rheum Dis. 2021. PMID: 33542104 Free PMC article.
Dersimelagon, a novel oral melanocortin 1 receptor agonist, demonstrates disease-modifying effects in preclinical models of systemic sclerosis.
Kondo M, Suzuki T, Kawano Y, Kojima S, Miyashiro M, Matsumoto A, Kania G, Błyszczuk P, Ross RL, Mulipa P, Del Galdo F, Zhang Y, Distler JHW. Kondo M, et al. Among authors: ross rl. Arthritis Res Ther. 2022 Sep 1;24(1):210. doi: 10.1186/s13075-022-02899-3. Arthritis Res Ther. 2022. PMID: 36050717 Free PMC article.
82 results