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Stress-induced mucin 13 reductions drive intestinal microbiome shifts and despair behaviors.
Rivet-Noor CR, Merchak AR, Render C, Gay NM, Beiter RM, Brown RM, Keeler A, Moreau GB, Li S, Olgun DG, Steigmeyer AD, Ofer R, Phan T, Vemuri K, Chen L, Mahoney KE, Shin JB, Malaker SA, Deppmann C, Verzi MP, Gaultier A. Rivet-Noor CR, et al. Among authors: malaker sa. Brain Behav Immun. 2024 Apr 4;119:665-680. doi: 10.1016/j.bbi.2024.03.028. Online ahead of print. Brain Behav Immun. 2024. PMID: 38579936 Free article.
Bump-and-hole engineering of human polypeptide N-acetylgalactosamine transferases to dissect their protein substrates and glycosylation sites in cells.
Calle B, Gonzalez-Rodriguez E, Mahoney KE, Cioce A, Bineva-Todd G, Tastan OY, Roustan C, Flynn H, Malaker SA, Schumann B. Calle B, et al. Among authors: malaker sa. STAR Protoc. 2023 Mar 17;4(1):101974. doi: 10.1016/j.xpro.2022.101974. Epub 2023 Jan 11. STAR Protoc. 2023. PMID: 36633947 Free PMC article.
The 2022 Nobel Prize in Chemistry-sweet!
Boyce M, Malaker SA, Riley NM, Kohler JJ. Boyce M, et al. Among authors: malaker sa. Glycobiology. 2023 Apr 19;33(3):178-181. doi: 10.1093/glycob/cwad016. Glycobiology. 2023. PMID: 36892406 No abstract available.
Loss of cis-PTase function in the liver promotes a highly penetrant form of fatty liver disease that rapidly transitions to hepatocellular carcinoma.
Singh AK, Chaube B, Citrin KM, Fowler JW, Lee S, Catarino J, Knight J, Lowery S, Shree S, Boutagy N, Ruz-Maldonado I, Harry K, Shanabrough M, Ross TT, Malaker S, Suárez Y, Fernández-Hernando C, Grabinska K, Sessa WC. Singh AK, et al. bioRxiv [Preprint]. 2023 Nov 15:2023.11.13.566870. doi: 10.1101/2023.11.13.566870. bioRxiv. 2023. PMID: 38014178 Free PMC article. Preprint.
Optimized mucin-selective enrichment strategy to probe the mucinome.
Mahoney KE, Chang V, Lucas TM, Maruszko K, Malaker SA. Mahoney KE, et al. Among authors: malaker sa. bioRxiv [Preprint]. 2023 Dec 18:2023.12.18.572204. doi: 10.1101/2023.12.18.572204. bioRxiv. 2023. PMID: 38187615 Free PMC article. Updated. Preprint.
Glycoproteomic landscape and structural dynamics of TIM family immune checkpoints enabled by mucinase SmE.
Chongsaritsinsuk J, Steigmeyer AD, Mahoney KE, Rosenfeld MA, Lucas TM, Smith CM, Li A, Ince D, Kearns FL, Battison AS, Hollenhorst MA, Judy Shon D, Tiemeyer KH, Attah V, Kwon C, Bertozzi CR, Ferracane MJ, Lemmon MA, Amaro RE, Malaker SA. Chongsaritsinsuk J, et al. Among authors: malaker sa. Nat Commun. 2023 Oct 4;14(1):6169. doi: 10.1038/s41467-023-41756-y. Nat Commun. 2023. PMID: 37794035 Free PMC article.
False-Positive Glycopeptide Identification via In-FAIMS Fragmentation.
Rangel-Angarita V, Mahoney KE, Kwon C, Sarker R, Lucas TM, Malaker SA. Rangel-Angarita V, et al. Among authors: malaker sa. JACS Au. 2023 Sep 12;3(9):2498-2509. doi: 10.1021/jacsau.3c00264. eCollection 2023 Sep 25. JACS Au. 2023. PMID: 37772174 Free PMC article.
Design of a mucin-selective protease for targeted degradation of cancer-associated mucins.
Pedram K, Shon DJ, Tender GS, Mantuano NR, Northey JJ, Metcalf KJ, Wisnovsky SP, Riley NM, Forcina GC, Malaker SA, Kuo A, George BM, Miller CL, Casey KM, Vilches-Moure JG, Ferracane MJ, Weaver VM, Läubli H, Bertozzi CR. Pedram K, et al. Among authors: malaker sa. Nat Biotechnol. 2024 Apr;42(4):597-607. doi: 10.1038/s41587-023-01840-6. Epub 2023 Aug 3. Nat Biotechnol. 2024. PMID: 37537499 Free PMC article.
47 results