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Skeletal muscle overexpression of nicotinamide phosphoribosyl transferase in mice coupled with voluntary exercise augments exercise endurance.
Costford SR, Brouwers B, Hopf ME, Sparks LM, Dispagna M, Gomes AP, Cornnell HH, Petucci C, Phelan P, Xie H, Yi F, Walter GA, Osborne TF, Sinclair DA, Mynatt RL, Ayala JE, Gardell SJ, Smith SR. Costford SR, et al. Among authors: hopf me. Mol Metab. 2018 Jan;7:1-11. doi: 10.1016/j.molmet.2017.10.012. Epub 2017 Nov 6. Mol Metab. 2018. PMID: 29146412 Free PMC article.
Boosting NAD+ with a small molecule that activates NAMPT.
Gardell SJ, Hopf M, Khan A, Dispagna M, Hampton Sessions E, Falter R, Kapoor N, Brooks J, Culver J, Petucci C, Ma CT, Cohen SE, Tanaka J, Burgos ES, Hirschi JS, Smith SR, Sergienko E, Pinkerton AB. Gardell SJ, et al. Nat Commun. 2019 Jul 19;10(1):3241. doi: 10.1038/s41467-019-11078-z. Nat Commun. 2019. PMID: 31324777 Free PMC article.
Human skeletal muscle tissue chip autonomous payload reveals changes in fiber type and metabolic gene expression due to spaceflight.
Parafati M, Giza S, Shenoy TS, Mojica-Santiago JA, Hopf M, Malany LK, Platt D, Moore I, Jacobs ZA, Kuehl P, Rexroat J, Barnett G, Schmidt CE, McLamb WT, Clements T, Coen PM, Malany S. Parafati M, et al. NPJ Microgravity. 2023 Sep 15;9(1):77. doi: 10.1038/s41526-023-00322-y. NPJ Microgravity. 2023. PMID: 37714852 Free PMC article.