Lebold TP - Search Results

1

Structure-Based Optimization of Selective and Brain Penetrant CK1δ Inhibitors for the Treatment of Circadian Disruptions.

McCarver S, Hanna L, Samant A, Thompson AA, Seierstad M, Saha A, Wu D, Lord B, Sutton SW, Shah V, Milligan CM, Wennerholm M, Shelton J, Lebold TP, Shireman BT. McCarver S, et al. Among authors: lebold tp. ACS Med Chem Lett. 2024 Mar 7;15(4):486-492. doi: 10.1021/acsmedchemlett.3c00523. eCollection 2024 Apr 11. ACS Med Chem Lett. 2024. PMID: 38628796

2

Synthesis of Highly Functionalized 4-Iodo-7-azaindazoles via Condensation/Diels-Alder/Retro-Diels-Alder Cyclization of Iodoalkynones and 2-Hydrazineylpyrimidines.

Swift EC, Sales ZS, Wu D, Matviitsuk A, Pippel DJ, Lebold TP. Swift EC, et al. Among authors: lebold tp. Org Lett. 2023 Dec 8;25(48):8711-8715. doi: 10.1021/acs.orglett.3c03481. Epub 2023 Nov 22. Org Lett. 2023. PMID: 37991557

3

Convergent synthesis of thiodiazole dioxides from simple ketones and amines through an unusual nitrogen-migration mechanism.

Punjajom K, Sinclair PP, Saha I, Seierstad M, Ameriks MK, García-Reynaga P, Lebold TP, Sarpong R. Punjajom K, et al. Among authors: lebold tp. Chem Sci. 2023 Nov 27;15(1):328-335. doi: 10.1039/d3sc04478e. eCollection 2023 Dec 20. Chem Sci. 2023. PMID: 38131085 Free PMC article.

4

A Unifying Synthesis Approach to the C₁₈-, C₁₉-, and C₂₀-Diterpenoid Alkaloids.

Kou KGM, Kulyk S, Marth CJ, Lee JC, Doering NA, Li BX, Gallego GM, Lebold TP, Sarpong R. Kou KGM, et al. Among authors: lebold tp. J Am Chem Soc. 2017 Oct 4;139(39):13882-13896. doi: 10.1021/jacs.7b07706. Epub 2017 Sep 20. J Am Chem Soc. 2017. PMID: 28858498 Free PMC article.

5

Syntheses of Denudatine Diterpenoid Alkaloids: Cochlearenine, N-Ethyl-1α-hydroxy-17-veratroyldictyzine, and Paniculamine.

Kou KG, Li BX, Lee JC, Gallego GM, Lebold TP, DiPasquale AG, Sarpong R. Kou KG, et al. Among authors: lebold tp. J Am Chem Soc. 2016 Aug 31;138(34):10830-3. doi: 10.1021/jacs.6b07268. Epub 2016 Aug 22. J Am Chem Soc. 2016. PMID: 27525345 Free PMC article.

6

Synthesis of the bridging framework of phragmalin-type limonoids.

Lebold TP, Gallego GM, Marth CJ, Sarpong R. Lebold TP, et al. Org Lett. 2012 Apr 20;14(8):2110-3. doi: 10.1021/ol300647k. Epub 2012 Apr 3. Org Lett. 2012. PMID: 22472049 Free PMC article.

7

A divergent approach to the synthesis of the yohimbinoid alkaloids venenatine and alstovenine.

Lebold TP, Wood JL, Deitch J, Lodewyk MW, Tantillo DJ, Sarpong R. Lebold TP, et al. Nat Chem. 2013 Feb;5(2):126-31. doi: 10.1038/nchem.1528. Epub 2012 Dec 23. Nat Chem. 2013. PMID: 23344433 Free PMC article.

8

A Benzyne Insertion Approach to Hetisine-Type Diterpenoid Alkaloids: Synthesis of Cossonidine (Davisine).

Kou KGM, Pflueger JJ, Kiho T, Morrill LC, Fisher EL, Clagg K, Lebold TP, Kisunzu JK, Sarpong R. Kou KGM, et al. Among authors: lebold tp. J Am Chem Soc. 2018 Jul 5;140(26):8105-8109. doi: 10.1021/jacs.8b05043. Epub 2018 Jun 19. J Am Chem Soc. 2018. PMID: 29889509 Free PMC article.

9

Skeletal Editing Approach to Bridge-Functionalized Bicyclo[1.1.1]pentanes from Azabicyclo[2.1.1]hexanes.

Wright BA, Matviitsuk A, Black MJ, García-Reynaga P, Hanna LE, Herrmann AT, Ameriks MK, Sarpong R, Lebold TP. Wright BA, et al. Among authors: lebold tp. J Am Chem Soc. 2023 May 24;145(20):10960-10966. doi: 10.1021/jacs.3c02616. Epub 2023 May 5. J Am Chem Soc. 2023. PMID: 37145091 Free PMC article.

10

Translational evaluation of novel selective orexin-1 receptor antagonist JNJ-61393215 in an experimental model for panic in rodents and humans.

Salvadore G, Bonaventure P, Shekhar A, Johnson PL, Lord B, Shireman BT, Lebold TP, Nepomuceno D, Dugovic C, Brooks S, Zuiker R, Bleys C, Tatikola K, Remmerie B, Jacobs GE, Schruers K, Moyer J, Nash A, Van Nueten LGM, Drevets WC. Salvadore G, et al. Among authors: lebold tp. Transl Psychiatry. 2020 Sep 7;10(1):308. doi: 10.1038/s41398-020-00937-9. Transl Psychiatry. 2020. PMID: 32895369 Free PMC article.

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