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Lipoarabinomannan modification as a source of phenotypic heterogeneity in host-adapted Mycobacterium abscessus isolates.
De K, Belardinelli JM, Pandurangan AP, Ehianeta T, Lian E, Palčeková Z, Lam H, Gonzalez-Juarrero M, Bryant JM, Blundell TL, Parkhill J, Floto RA, Lowary TL, Wheat WH, Jackson M. De K, et al. Among authors: wheat wh. Proc Natl Acad Sci U S A. 2024 Apr 23;121(17):e2403206121. doi: 10.1073/pnas.2403206121. Epub 2024 Apr 17. Proc Natl Acad Sci U S A. 2024. PMID: 38630725
Clinically relevant mutations in the PhoR sensor kinase of host-adapted Mycobacterium abscessus isolates impact response to acidic pH and virulence.
Belardinelli JM, Arora D, Avanzi C, Wheat WH, Bryant JM, Spencer JS, Blundell TL, Parkhill J, Floto RA, Jackson M. Belardinelli JM, et al. Among authors: wheat wh. Microbiol Spectr. 2023 Dec 12;11(6):e0158823. doi: 10.1128/spectrum.01588-23. Epub 2023 Oct 24. Microbiol Spectr. 2023. PMID: 37874174 Free PMC article.
Impact of Methylthioxylose Substituents on the Biological Activities of Lipomannan and Lipoarabinomannan in Mycobacterium tuberculosis.
Palčeková Z, De K, Angala SK, Gilleron M, Zuberogoitia S, Gouxette L, Soto-Ojeda M, Gonzalez-Juarrero M, Obregón-Henao A, Nigou J, Wheat WH, Jackson M. Palčeková Z, et al. Among authors: wheat wh. ACS Infect Dis. 2024 Apr 12;10(4):1379-1390. doi: 10.1021/acsinfecdis.4c00079. Epub 2024 Mar 21. ACS Infect Dis. 2024. PMID: 38511206
The cell envelope glycoconjugates of Mycobacterium tuberculosis.
Angala SK, Belardinelli JM, Huc-Claustre E, Wheat WH, Jackson M. Angala SK, et al. Among authors: wheat wh. Crit Rev Biochem Mol Biol. 2014 Sep-Oct;49(5):361-99. doi: 10.3109/10409238.2014.925420. Epub 2014 Jun 10. Crit Rev Biochem Mol Biol. 2014. PMID: 24915502 Free PMC article. Review.
Role of succinyl substituents in the mannose-capping of lipoarabinomannan and control of inflammation in Mycobacterium tuberculosis infection.
Palčeková Z, Obregón-Henao A, De K, Walz A, Lam H, Philp J, Angala SK, Patterson J, Pearce C, Zuberogoitia S, Avanzi C, Nigou J, McNeil M, Muñoz Gutiérrez JF, Gilleron M, Wheat WH, Gonzalez-Juarrero M, Jackson M. Palčeková Z, et al. Among authors: wheat wh. PLoS Pathog. 2023 Sep 5;19(9):e1011636. doi: 10.1371/journal.ppat.1011636. eCollection 2023 Sep. PLoS Pathog. 2023. PMID: 37669276 Free PMC article.
Long-term survival and virulence of Mycobacterium leprae in amoebal cysts.
Wheat WH, Casali AL, Thomas V, Spencer JS, Lahiri R, Williams DL, McDonnell GE, Gonzalez-Juarrero M, Brennan PJ, Jackson M. Wheat WH, et al. PLoS Negl Trop Dis. 2014 Dec 18;8(12):e3405. doi: 10.1371/journal.pntd.0003405. eCollection 2014 Dec. PLoS Negl Trop Dis. 2014. PMID: 25521850 Free PMC article.
The presence of a galactosamine substituent on the arabinogalactan of Mycobacterium tuberculosis abrogates full maturation of human peripheral blood monocyte-derived dendritic cells and increases secretion of IL-10.
Wheat WH, Dhouib R, Angala SK, Larrouy-Maumus G, Dobos K, Nigou J, Spencer JS, Jackson M. Wheat WH, et al. Tuberculosis (Edinb). 2015 Jul;95(4):476-89. doi: 10.1016/j.tube.2015.04.002. Epub 2015 May 14. Tuberculosis (Edinb). 2015. PMID: 26048627 Free PMC article.
37 results