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Page 1
Single Cell Analysis of Treatment-Resistant Prostate Cancer: Implications of Cell State Changes for Cell Surface Antigen Targeted Therapies.
Zaidi S, Park J, Chan JM, Roudier MP, Zhao JL, Gopalan A, Wadosky KM, Patel RA, Sayar E, Karthaus WR, Henry Kates D, Chaudhary O, Xu T, Masilionis I, Mazutis L, Chaligné R, Obradovic A, Linkov I, Barlas A, Jungbluth A, Rekhtman N, Silber J, Manova-Todorova K, Watson PA, True LD, Morrissey CM, Scher HI, Rathkopf D, Morris MJ, Goodrich DW, Choi J, Nelson PS, Haffner MC, Sawyers CL. Zaidi S, et al. Among authors: manova todorova k. bioRxiv [Preprint]. 2024 Apr 12:2024.04.09.588340. doi: 10.1101/2024.04.09.588340. bioRxiv. 2024. PMID: 38645034 Free PMC article. Preprint.
Tumorigenesis driven by the BRAFV600E oncoprotein requires secondary mutations that overcome its feedback inhibition of migration and invasion.
Gadal S, Boyer JA, Roy SF, Outmezguine NA, Sharma M, Li H, Fan N, Chan E, Romin Y, Barlas A, Chang Q, Pancholi P, Timaul NM, Overholtzer M, Yaeger R, Manova-Todorova K, de Stanchina E, Bosenberg M, Rosen N. Gadal S, et al. Among authors: manova todorova k. bioRxiv [Preprint]. 2024 Apr 20:2023.11.21.568071. doi: 10.1101/2023.11.21.568071. bioRxiv. 2024. PMID: 38659913 Free PMC article. Preprint.
Membrane-derived particles shed by PSMA-positive cells function as pro-angiogenic stimuli in tumors.
Machado CML, Skubal M, Haedicke K, Silva FP, Stater EP, Silva TLAO, Costa ET, Masotti C, Otake AH, Andrade LNS, Junqueira MS, Hsu HT, Das S, Larney BM, Pratt EC, Romin Y, Fan N, Manova-Todorova K, Pomper M, Grimm J. Machado CML, et al. Among authors: manova todorova k. J Control Release. 2023 Dec;364:312-325. doi: 10.1016/j.jconrel.2023.10.038. Epub 2023 Nov 2. J Control Release. 2023. PMID: 37884210
Therapy-Induced Senescence Contributes to the Efficacy of Abemaciclib in Patients with Dedifferentiated Liposarcoma.
Gleason CE, Dickson MA, Klein Dooley ME, Antonescu CR, Gularte-Mérida R, Benitez M, Delgado JI, Kataru RP, Tan MWY, Bradic M, Adamson TE, Seier K, Richards AL, Palafox M, Chan E, D'Angelo SP, Gounder MM, Keohan ML, Kelly CM, Chi P, Movva S, Landa J, Crago AM, Donoghue MTA, Qin LX, Serra V, Turkekul M, Barlas A, Firester DM, Manova-Todorova K, Mehrara BJ, Kovatcheva M, Tan NS, Singer S, Tap WD, Koff A. Gleason CE, et al. Among authors: manova todorova k. Clin Cancer Res. 2024 Feb 16;30(4):703-718. doi: 10.1158/1078-0432.CCR-23-2378. Clin Cancer Res. 2024. PMID: 37695642 Free PMC article.
Systems-level analyses of protein-protein interaction network dysfunctions via epichaperomics identify cancer-specific mechanisms of stress adaptation.
Rodina A, Xu C, Digwal CS, Joshi S, Patel Y, Santhaseela AR, Bay S, Merugu S, Alam A, Yan P, Yang C, Roychowdhury T, Panchal P, Shrestha L, Kang Y, Sharma S, Almodovar J, Corben A, Alpaugh ML, Modi S, Guzman ML, Fei T, Taldone T, Ginsberg SD, Erdjument-Bromage H, Neubert TA, Manova-Todorova K, Tsou MB, Young JC, Wang T, Chiosis G. Rodina A, et al. Among authors: manova todorova k. Nat Commun. 2023 Jun 23;14(1):3742. doi: 10.1038/s41467-023-39241-7. Nat Commun. 2023. PMID: 37353488 Free PMC article.
Allosteric interactions prime androgen receptor dimerization and activation.
Wasmuth EV, Broeck AV, LaClair JR, Hoover EA, Lawrence KE, Paknejad N, Pappas K, Matthies D, Wang B, Feng W, Watson PA, Zinder JC, Karthaus WR, de la Cruz MJ, Hite RK, Manova-Todorova K, Yu Z, Weintraub ST, Klinge S, Sawyers CL. Wasmuth EV, et al. Among authors: manova todorova k. Mol Cell. 2022 Jun 2;82(11):2021-2031.e5. doi: 10.1016/j.molcel.2022.03.035. Epub 2022 Apr 20. Mol Cell. 2022. PMID: 35447082 Free PMC article.
Biopsy and Margins Optimize Outcomes after Thermal Ablation of Colorectal Liver Metastases.
Vasiniotis Kamarinos N, Vakiani E, Gonen M, Kemeny NE, Sigel C, Saltz LB, Brown KT, Covey AM, Erinjeri JP, Brody LA, Ziv E, Yarmohammadi H, Kunin H, Barlas A, Petre EN, Kingham PT, D'Angelica MI, Manova-Todorova K, Solomon SB, Sofocleous CT. Vasiniotis Kamarinos N, et al. Among authors: manova todorova k. Cancers (Basel). 2022 Jan 29;14(3):693. doi: 10.3390/cancers14030693. Cancers (Basel). 2022. PMID: 35158963 Free PMC article.
Targeting S100A9-ALDH1A1-Retinoic Acid Signaling to Suppress Brain Relapse in EGFR-Mutant Lung Cancer.
Biswas AK, Han S, Tai Y, Ma W, Coker C, Quinn SA, Shakri AR, Zhong TJ, Scholze H, Lagos GG, Mela A, Manova-Todorova K, de Stanchina E, Ferrando AA, Mendelsohn C, Canoll P, Yu HA, Paik PK, Saqi A, Shu CA, Kris MG, Massague J, Acharyya S. Biswas AK, et al. Among authors: manova todorova k. Cancer Discov. 2022 Apr 1;12(4):1002-1021. doi: 10.1158/2159-8290.CD-21-0910. Cancer Discov. 2022. PMID: 35078784 Free PMC article.
Immunofluorescence Assay of Ablated Colorectal Liver Metastases: The Frozen Section of Image-Guided Tumor Ablation?
Vasiniotis Kamarinos N, Vakiani E, Fujisawa S, Gonen M, Fan N, Romin Y, Do RKG, Ziv E, Erinjeri JP, Petre EN, Sotirchos VS, Camacho JC, Solomon SB, Manova-Todorova K, Sofocleous CT. Vasiniotis Kamarinos N, et al. Among authors: manova todorova k. J Vasc Interv Radiol. 2022 Mar;33(3):308-315.e1. doi: 10.1016/j.jvir.2021.11.008. Epub 2021 Nov 17. J Vasc Interv Radiol. 2022. PMID: 34800623 Free PMC article.
64 results