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Chemical tools to define and manipulate interferon-inducible Ubl protease USP18.
Davis GJ, Omole AO, Jung Y, Rut W, Holewinski R, Suazo KF, Kim HR, Yang M, Andresson T, Drag M, Yoo E. Davis GJ, et al. Among authors: andresson t. bioRxiv [Preprint]. 2024 Apr 8:2024.04.08.588544. doi: 10.1101/2024.04.08.588544. bioRxiv. 2024. PMID: 38645224 Free PMC article. Preprint.
Loss of NAT10 disrupts enhancer organization via p300 mislocalization and suppresses transcription of genes necessary for metastasis progression.
Amin R, Ha NH, Qiu T, Holewinski R, Lam KC, Lopès A, Liu H, Tran AD, Lee MP, Gamage ST, Andresson T, Goldszmid RS, Meier JL, Hunter KW. Amin R, et al. Among authors: andresson t. bioRxiv [Preprint]. 2024 Jan 29:2024.01.24.577116. doi: 10.1101/2024.01.24.577116. bioRxiv. 2024. PMID: 38410432 Free PMC article. Preprint.
A structure-based designed small molecule depletes hRpn13Pru and a select group of KEN box proteins.
Lu X, Chandravanshi M, Sabbasani VR, Gaikwad S, Hughitt VK, Gyabaah-Kessie N, Scroggins BT, Das S, Myint W, Clapp ME, Schwieters CD, Dyba MA, Bolhuis DL, Koscielniak JW, Andresson T, Emanuele MJ, Brown NG, Matsuo H, Chari R, Citrin DE, Mock BA, Swenson RE, Walters KJ. Lu X, et al. Among authors: andresson t. Nat Commun. 2024 Mar 20;15(1):2485. doi: 10.1038/s41467-024-46644-7. Nat Commun. 2024. PMID: 38509117 Free PMC article.
Rewiring of RNA methylation by the oncometabolite fumarate in renal cell carcinoma.
Fitzsimmons CM, Mandler MD, Lunger JC, Chan D, Maligireddy SS, Schmiechen AC, Gamage ST, Link C, Jenkins LM, Chan K, Andresson T, Crooks DR, Meier JL, Linehan WM, Batista PJ. Fitzsimmons CM, et al. Among authors: andresson t. NAR Cancer. 2024 Feb 7;6(1):zcae004. doi: 10.1093/narcan/zcae004. eCollection 2024 Mar. NAR Cancer. 2024. PMID: 38328795 Free PMC article.
hRpn13 shapes the proteome and transcriptome through epigenetic factors HDAC8, PADI4, and transcription factor NF-κB p50.
Osei-Amponsa V, Chandravanshi M, Lu X, Magidson V, Das S, Andresson T, Dyba M, Sabbasani VR, Swenson RE, Fromont C, Shrestha B, Zhao Y, Clapp ME, Chari R, Walters KJ. Osei-Amponsa V, et al. Among authors: andresson t. Mol Cell. 2024 Feb 1;84(3):522-537.e8. doi: 10.1016/j.molcel.2023.11.035. Epub 2023 Dec 26. Mol Cell. 2024. PMID: 38151017
83 results