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The amino acid sensor GCN2 suppresses terminal oligopyrimidine (TOP) mRNA translation via La-related protein 1 (LARP1).
Farooq Z, Kusuma F, Burke P, Dufour CR, Lee D, Tabatabaei N, Toboz P, Radovani E, Greenblatt JF, Rehman J, Class J, Khoutorsky A, Fonseca BD, Richner JM, Mercier E, Bourque G, Giguère V, Subramaniam AR, Han J, Tahmasebi S. Farooq Z, et al. Among authors: subramaniam ar. J Biol Chem. 2022 Sep;298(9):102277. doi: 10.1016/j.jbc.2022.102277. Epub 2022 Jul 19. J Biol Chem. 2022. PMID: 35863436 Free PMC article.
Coordinated missplicing of TMEM14C and ABCB7 causes ring sideroblast formation in SF3B1-mutant myelodysplastic syndrome.
Clough CA, Pangallo J, Sarchi M, Ilagan JO, North K, Bergantinos R, Stolla MC, Naru J, Nugent P, Kim E, Stirewalt DL, Subramaniam AR, Abdel-Wahab O, Abkowitz JL, Bradley RK, Doulatov S. Clough CA, et al. Among authors: subramaniam ar. Blood. 2022 Mar 31;139(13):2038-2049. doi: 10.1182/blood.2021012652. Blood. 2022. PMID: 34861039 Free PMC article.
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