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Single molecule array measures of LRRK2 kinase activity in serum link Parkinson's disease severity to peripheral inflammation.
Yuan Y, Li H, Sreeram K, Malankhanova T, Boddu R, Strader S, Chang A, Bryant N, Yacoubian TA, Standaert DG, Erb M, Moore DJ, Sanders LH, Lutz MW, Velmeshev D, West AB. Yuan Y, et al. Among authors: moore dj. bioRxiv [Preprint]. 2024 Apr 17:2024.04.15.589570. doi: 10.1101/2024.04.15.589570. bioRxiv. 2024. PMID: 38659797 Free PMC article. Preprint.
LRRK2 secretion in exosomes is regulated by 14-3-3.
Fraser KB, Moehle MS, Daher JP, Webber PJ, Williams JY, Stewart CA, Yacoubian TA, Cowell RM, Dokland T, Ye T, Chen D, Siegal GP, Galemmo RA, Tsika E, Moore DJ, Standaert DG, Kojima K, Mobley JA, West AB. Fraser KB, et al. Among authors: moore dj. Hum Mol Genet. 2013 Dec 15;22(24):4988-5000. doi: 10.1093/hmg/ddt346. Epub 2013 Jul 25. Hum Mol Genet. 2013. PMID: 23886663 Free PMC article.
Evaluation of Current Methods to Detect Cellular Leucine-Rich Repeat Kinase 2 (LRRK2) Kinase Activity.
Fernández B, Chittoor-Vinod VG, Kluss JH, Kelly K, Bryant N, Nguyen APT, Bukhari SA, Smith N, Lara Ordóñez AJ, Fdez E, Chartier-Harlin MC, Montine TJ, Wilson MA, Moore DJ, West AB, Cookson MR, Nichols RJ, Hilfiker S. Fernández B, et al. Among authors: moore dj. J Parkinsons Dis. 2022;12(5):1423-1447. doi: 10.3233/JPD-213128. J Parkinsons Dis. 2022. PMID: 35599495 Free PMC article.
Molecular pathophysiology of Parkinson's disease.
Moore DJ, West AB, Dawson VL, Dawson TM. Moore DJ, et al. Annu Rev Neurosci. 2005;28:57-87. doi: 10.1146/annurev.neuro.28.061604.135718. Annu Rev Neurosci. 2005. PMID: 16022590 Review.
1,002 results