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Germline Testing identifies Pathogenic/Likely Pathogenic Variants in Patients with Pancreatic Neuroendocrine Tumors.
Mohindroo C, Baydogan S, Agarwal P, Wright RD, Prakash LR, Mork ME, Klein AP, Laheru DA, Maxwell JE, Katz MHG, Dasari A, Kim MP, He J, McAllister F, De Jesus-Acosta A. Mohindroo C, et al. Among authors: laheru da. Cancer Prev Res (Phila). 2024 Apr 25. doi: 10.1158/1940-6207.CAPR-23-0483. Online ahead of print. Cancer Prev Res (Phila). 2024. PMID: 38662083
Long-term survival benefit of upfront chemotherapy in patients with newly diagnosed borderline resectable pancreatic cancer.
Shrestha B, Sun Y, Faisal F, Kim V, Soares K, Blair A, Herman JM, Narang A, Dholakia AS, Rosati L, Hacker-Prietz A, Chen L, Laheru DA, De Jesus-Acosta A, Le DT, Donehower R, Azad N, Diaz LA, Murphy A, Lee V, Fishman EK, Hruban RH, Liang T, Cameron JL, Makary M, Weiss MJ, Ahuja N, He J, Wolfgang CL, Huang CY, Zheng L. Shrestha B, et al. Among authors: laheru da. Cancer Med. 2017 Jul;6(7):1552-1562. doi: 10.1002/cam4.1104. Epub 2017 Jun 21. Cancer Med. 2017. PMID: 28639410 Free PMC article.
RAD51B Harbors Germline Mutations Associated With Pancreatic Ductal Adenocarcinoma.
Xie F, Ding D, Lin C, Cunningham D, Wright M, Javed AA, Azad N, Lee V, Donehower R, De Jesus-Acosta A, Le DT, Pishvaian M, Shin EJ, Lennon AM, Khashab M, Singh V, Klein AP, Roberts NJ, Hacker-Prietz A, McPhaul T, Burkhart RA, Burns WR, Narang A, Zaheer A, Fishman EK, Thompson ED, Anders R, Yu J, He J, Wolfgang CL, Zheng L, Liu D, Wu K, Laheru DA. Xie F, et al. Among authors: laheru da. JCO Precis Oncol. 2022 Jun;6:e2100404. doi: 10.1200/PO.21.00404. JCO Precis Oncol. 2022. PMID: 35737913 Free PMC article.
Elevated cancer mortality in the relatives of patients with pancreatic cancer.
Wang L, Brune KA, Visvanathan K, Laheru D, Herman J, Wolfgang C, Schulick R, Cameron JL, Goggins M, Hruban RH, Klein AP. Wang L, et al. Cancer Epidemiol Biomarkers Prev. 2009 Nov;18(11):2829-34. doi: 10.1158/1055-9965.EPI-09-0557. Epub 2009 Oct 20. Cancer Epidemiol Biomarkers Prev. 2009. PMID: 19843679 Free PMC article.
Phase 2 study of vismodegib, a hedgehog inhibitor, combined with gemcitabine and nab-paclitaxel in patients with untreated metastatic pancreatic adenocarcinoma.
De Jesus-Acosta A, Sugar EA, O'Dwyer PJ, Ramanathan RK, Von Hoff DD, Rasheed Z, Zheng L, Begum A, Anders R, Maitra A, McAllister F, Rajeshkumar NV, Yabuuchi S, de Wilde RF, Batukbhai B, Sahin I, Laheru DA. De Jesus-Acosta A, et al. Among authors: laheru da. Br J Cancer. 2020 Feb;122(4):498-505. doi: 10.1038/s41416-019-0683-3. Epub 2019 Dec 20. Br J Cancer. 2020. PMID: 31857726 Free PMC article. Clinical Trial.
Challenges of the current precision medicine approach for pancreatic cancer: A single institution experience between 2013 and 2017.
Ding D, Javed AA, Cunningham D, Teinor J, Wright M, Javed ZN, Wilt C, Parish L, Hodgin M, Ryan A, Judkins C, McIntyre K, Klein R, Azad N, Lee V, Donehower R, De Jesus-Acosta A, Murphy A, Le DT, Shin EJ, Lennon AM, Khashab M, Singh V, Klein AP, Roberts NJ, Hacker-Prietz A, Manos L, Walsh C, Groshek L, Brown C, Yuan C, Blair AB, Groot V, Gemenetzis G, Yu J, Weiss MJ, Burkhart RA, Burns WR, He J, Cameron JL, Narang A, Zaheer A, Fishman EK, Thompson ED, Anders R, Hruban RH, Jaffee E, Wolfgang CL, Zheng L, Laheru DA. Ding D, et al. Among authors: laheru da. Cancer Lett. 2021 Jan 28;497:221-228. doi: 10.1016/j.canlet.2020.10.039. Epub 2020 Oct 28. Cancer Lett. 2021. PMID: 33127389 Free PMC article. Clinical Trial.
High local failure rates despite high margin-negative resection rates in a cohort of borderline resectable and locally advanced pancreatic cancer patients treated with stereotactic body radiation therapy following multi-agent chemotherapy.
Hill C, Sehgal S, Fu W, Hu C, Reddy A, Thompson E, Hacker-Prietz A, Le D, De Jesus-Acosta A, Lee V, Zheng L, Laheru DA, Burns W, Weiss M, Wolfgang C, He J, Herman JM, Meyer J, Narang A. Hill C, et al. Among authors: laheru da. Cancer Med. 2022 Apr;11(7):1659-1668. doi: 10.1002/cam4.4527. Epub 2022 Feb 10. Cancer Med. 2022. PMID: 35142085 Free PMC article.
199 results