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Design, Synthesis, and Investigation of the Pharmacokinetics and Anticancer Activities of Indenoisoquinoline Derivatives That Stabilize the G-Quadruplex in the MYC Promoter and Inhibit Topoisomerase I.
Han Y, Buric A, Chintareddy V, DeMoss M, Chen L, Dickerhoff J, De Dios R, Chand P, Riggs R, Yang D, Cushman M. Han Y, et al. Among authors: cushman m. J Med Chem. 2024 May 9;67(9):7006-7032. doi: 10.1021/acs.jmedchem.3c02303. Epub 2024 Apr 26. J Med Chem. 2024. PMID: 38668707
Design and Synthesis of Chlorinated and Fluorinated 7-Azaindenoisoquinolines as Potent Cytotoxic Anticancer Agents That Inhibit Topoisomerase I.
Elsayed MSA, Su Y, Wang P, Sethi T, Agama K, Ravji A, Redon CE, Kiselev E, Horzmann KA, Freeman JL, Pommier Y, Cushman M. Elsayed MSA, et al. Among authors: cushman m. J Med Chem. 2017 Jul 13;60(13):5364-5376. doi: 10.1021/acs.jmedchem.6b01870. Epub 2017 Jun 28. J Med Chem. 2017. PMID: 28657311 Free PMC article.
1,167 results