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Design of Cytotoxic T Cell Epitopes by Machine Learning of Human Degrons.
Truex NL, Mohapatra S, Melo M, Rodriguez J, Li N, Abraham W, Sementa D, Touti F, Keskin DB, Wu CJ, Irvine DJ, Gómez-Bombarelli R, Pentelute BL. Truex NL, et al. Among authors: irvine dj. ACS Cent Sci. 2024 Mar 6;10(4):793-802. doi: 10.1021/acscentsci.3c01544. eCollection 2024 Apr 24. ACS Cent Sci. 2024. PMID: 38680558 Free PMC article.
Vaccine delivery with microneedle skin patches in nonhuman primates.
DeMuth PC, Li AV, Abbink P, Liu J, Li H, Stanley KA, Smith KM, Lavine CL, Seaman MS, Kramer JA, Miller AD, Abraham W, Suh H, Elkhader J, Hammond PT, Barouch DH, Irvine DJ. DeMuth PC, et al. Among authors: irvine dj. Nat Biotechnol. 2013 Dec;31(12):1082-5. doi: 10.1038/nbt.2759. Nat Biotechnol. 2013. PMID: 24316643 Free PMC article. No abstract available.
Sustained antigen availability during germinal center initiation enhances antibody responses to vaccination.
Tam HH, Melo MB, Kang M, Pelet JM, Ruda VM, Foley MH, Hu JK, Kumari S, Crampton J, Baldeon AD, Sanders RW, Moore JP, Crotty S, Langer R, Anderson DG, Chakraborty AK, Irvine DJ. Tam HH, et al. Among authors: irvine dj. Proc Natl Acad Sci U S A. 2016 Oct 25;113(43):E6639-E6648. doi: 10.1073/pnas.1606050113. Epub 2016 Oct 4. Proc Natl Acad Sci U S A. 2016. PMID: 27702895 Free PMC article.
Eradication of large established tumors in mice by combination immunotherapy that engages innate and adaptive immune responses.
Moynihan KD, Opel CF, Szeto GL, Tzeng A, Zhu EF, Engreitz JM, Williams RT, Rakhra K, Zhang MH, Rothschilds AM, Kumari S, Kelly RL, Kwan BH, Abraham W, Hu K, Mehta NK, Kauke MJ, Suh H, Cochran JR, Lauffenburger DA, Wittrup KD, Irvine DJ. Moynihan KD, et al. Among authors: irvine dj. Nat Med. 2016 Dec;22(12):1402-1410. doi: 10.1038/nm.4200. Epub 2016 Oct 24. Nat Med. 2016. PMID: 27775706 Free PMC article.
310 results