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Efficacy and safety of the muscarinic receptor agonist KarXT (xanomeline-trospium) in schizophrenia (EMERGENT-2) in the USA: results from a randomised, double-blind, placebo-controlled, flexible-dose phase 3 trial.
Kaul I, Sawchak S, Correll CU, Kakar R, Breier A, Zhu H, Miller AC, Paul SM, Brannan SK. Kaul I, et al. Among authors: brannan sk. Lancet. 2024 Jan 13;403(10422):160-170. doi: 10.1016/S0140-6736(23)02190-6. Epub 2023 Dec 14. Lancet. 2024. PMID: 38104575 Clinical Trial.
Muscarinic Receptor Activators as Novel Treatments for Schizophrenia.
Paul SM, Yohn SE, Brannan SK, Neugebauer NM, Breier A. Paul SM, et al. Among authors: brannan sk. Biol Psychiatry. 2024 Mar 25:S0006-3223(24)01173-9. doi: 10.1016/j.biopsych.2024.03.014. Online ahead of print. Biol Psychiatry. 2024. PMID: 38537670 Free article. Review.
Antipsychotic Efficacy of KarXT (Xanomeline-Trospium): Post Hoc Analysis of Positive and Negative Syndrome Scale Categorical Response Rates, Time Course of Response, and Symptom Domains of Response in a Phase 2 Study.
Weiden PJ, Breier A, Kavanagh S, Miller AC, Brannan SK, Paul SM. Weiden PJ, et al. Among authors: brannan sk. J Clin Psychiatry. 2022 May 11;83(3):21m14316. doi: 10.4088/JCP.21m14316. J Clin Psychiatry. 2022. PMID: 35552528 Free article. Clinical Trial.
Clinical Trial of New Drug for Schizophrenia. Reply.
Paul SM, Breier A, Lieberman JA, Brannan SK, Sawchak S, Miller AC. Paul SM, et al. Among authors: brannan sk. N Engl J Med. 2021 Jun 24;384(25):e105. doi: 10.1056/NEJMc2104965. N Engl J Med. 2021. PMID: 34161716 No abstract available.
36 results