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Small-molecule inhibition of the METTL3/METTL14 complex suppresses neuroblastoma tumor growth and promotes differentiation.
Pomaville M, Chennakesavalu M, Wang P, Jiang Z, Sun HL, Ren P, Borchert R, Gupta V, Ye C, Ge R, Zhu Z, Brodnik M, Zhong Y, Moore K, Salwen H, George RE, Krajewska M, Chlenski A, Applebaum MA, He C, Cohn SL. Pomaville M, et al. Among authors: applebaum ma. Cell Rep. 2024 May 28;43(5):114165. doi: 10.1016/j.celrep.2024.114165. Epub 2024 Apr 30. Cell Rep. 2024. PMID: 38691450 Free article.
5-Hydroxymethylcytosine Profiles Are Prognostic of Outcome in Neuroblastoma and Reveal Transcriptional Networks That Correlate With Tumor Phenotype.
Applebaum MA, Barr EK, Karpus J, Nie J, Zhang Z, Armstrong AE, Uppal S, Sukhanova M, Zhang W, Chlenski A, Salwen HR, Wilkinson E, Dobratic M, Grossman R, Godley LA, Stranger BE, He C, Cohn SL. Applebaum MA, et al. JCO Precis Oncol. 2019;3:PO.18.00402. doi: 10.1200/PO.18.00402. Epub 2019 May 16. JCO Precis Oncol. 2019. PMID: 31179414 Free PMC article.
5-Hydroxymethylcytosine Profiles in Circulating Cell-Free DNA Associate with Disease Burden in Children with Neuroblastoma.
Applebaum MA, Barr EK, Karpus J, West-Szymanski DC, Oliva M, Sokol EA, Zhang S, Zhang Z, Zhang W, Chlenski A, Salwen HR, Wilkinson E, Dobratic M, Grossman RL, Godley LA, Stranger BE, He C, Cohn SL. Applebaum MA, et al. Clin Cancer Res. 2020 Mar 15;26(6):1309-1317. doi: 10.1158/1078-0432.CCR-19-2829. Epub 2019 Dec 18. Clin Cancer Res. 2020. PMID: 31852832 Free PMC article.
Emerging and investigational therapies for neuroblastoma.
Applebaum MA, Desai AV, Glade Bender JL, Cohn SL. Applebaum MA, et al. Expert Opin Orphan Drugs. 2017;5(4):355-368. doi: 10.1080/21678707.2017.1304212. Epub 2017 Mar 17. Expert Opin Orphan Drugs. 2017. PMID: 29062613 Free PMC article.
58 results