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Oxidative phosphorylation regulates B cell effector cytokines and promotes inflammation in multiple sclerosis.
Li R, Lei Y, Rezk A, Diego A Espinoza, Wang J, Feng H, Zhang B, Barcelos IP, Zhang H, Yu J, Huo X, Zhu F, Yang C, Tang H, Goldstein AC, Banwell BL, Hakonarson H, Xu H, Mingueneau M, Sun B, Li H, Bar-Or A. Li R, et al. Among authors: diego a espinoza. Sci Immunol. 2024 May 3;9(95):eadk0865. doi: 10.1126/sciimmunol.adk0865. Epub 2024 May 3. Sci Immunol. 2024. PMID: 38701189
Comparison of busulfan and total body irradiation conditioning on hematopoietic clonal dynamics following lentiviral gene transfer in rhesus macaques.
Abraham DM, Lozano RJ, Guitart X, Liang JA, Mortlock RD, Espinoza DA, Fan X, Krouse A, Bonifacino A, Hong SG, Singh K, Tisdale JF, Wu C, Dunbar CE. Abraham DM, et al. Among authors: espinoza da. Mol Ther Methods Clin Dev. 2022 Dec 6;28:62-75. doi: 10.1016/j.omtm.2022.12.001. eCollection 2023 Mar 9. Mol Ther Methods Clin Dev. 2022. PMID: 36620072 Free PMC article.
Immune aging in multiple sclerosis is characterized by abnormal CD4 T cell activation and increased frequencies of cytotoxic CD4 T cells with advancing age.
Zuroff L, Rezk A, Shinoda K, Espinoza DA, Elyahu Y, Zhang B, Chen AA, Shinohara RT, Jacobs D, Alcalay RN, Tropea TF, Chen-Plotkin A, Monsonego A, Li R, Bar-Or A. Zuroff L, et al. Among authors: espinoza da. EBioMedicine. 2022 Aug;82:104179. doi: 10.1016/j.ebiom.2022.104179. Epub 2022 Jul 19. EBioMedicine. 2022. PMID: 35868128 Free PMC article.
Cellular and humoral immune responses following SARS-CoV-2 mRNA vaccination in patients with multiple sclerosis on anti-CD20 therapy.
Apostolidis SA, Kakara M, Painter MM, Goel RR, Mathew D, Lenzi K, Rezk A, Patterson KR, Espinoza DA, Kadri JC, Markowitz DM, E Markowitz C, Mexhitaj I, Jacobs D, Babb A, Betts MR, Prak ETL, Weiskopf D, Grifoni A, Lundgreen KA, Gouma S, Sette A, Bates P, Hensley SE, Greenplate AR, Wherry EJ, Li R, Bar-Or A. Apostolidis SA, et al. Among authors: espinoza da. Nat Med. 2021 Nov;27(11):1990-2001. doi: 10.1038/s41591-021-01507-2. Epub 2021 Sep 14. Nat Med. 2021. PMID: 34522051 Free PMC article.
Interrogation of clonal tracking data using barcodetrackR.
Espinoza DA, Mortlock RD, Koelle SJ, Wu C, Dunbar CE. Espinoza DA, et al. Nat Comput Sci. 2021 Apr;1(4):280-289. doi: 10.1038/s43588-021-00057-4. Epub 2021 Apr 26. Nat Comput Sci. 2021. PMID: 37621673 Free PMC article.
Comparative engraftment and clonality of macaque HSPCs expanded on human umbilical vein endothelial cells versus non-expanded cells.
Srivastava SK, Truitt LL, Wu C, Glaser A, Nolan DJ, Ginsberg M, Espinoza DA, Koelle S, Yabe IM, Yu KR, Hong S, Sellers S, Krouse A, Bonifacino A, Metzger M, Dagur PK, Donahue RE, Dunbar CE, Panch SR. Srivastava SK, et al. Among authors: espinoza da. Mol Ther Methods Clin Dev. 2021 Feb 15;20:703-715. doi: 10.1016/j.omtm.2021.02.009. eCollection 2021 Mar 12. Mol Ther Methods Clin Dev. 2021. PMID: 33738325 Free PMC article.
Clonal tracking of erythropoiesis in rhesus macaques.
Fan X, Wu C, Truitt LL, Espinoza DA, Sellers S, Bonifacino A, Zhou Y, Cordes SF, Krouse A, Metzger M, Donahue RE, Lu R, Dunbar CE. Fan X, et al. Among authors: espinoza da. Haematologica. 2020 Jul;105(7):1813-1824. doi: 10.3324/haematol.2019.231811. Epub 2019 Oct 3. Haematologica. 2020. PMID: 31582555 Free PMC article.
Aberrant Clonal Hematopoiesis following Lentiviral Vector Transduction of HSPCs in a Rhesus Macaque.
Espinoza DA, Fan X, Yang D, Cordes SF, Truitt LL, Calvo KR, Yabe IM, Demirci S, Hope KJ, Hong SG, Krouse A, Metzger M, Bonifacino A, Lu R, Uchida N, Tisdale JF, Wu X, DeRavin SS, Malech HL, Donahue RE, Wu C, Dunbar CE. Espinoza DA, et al. Mol Ther. 2019 Jun 5;27(6):1074-1086. doi: 10.1016/j.ymthe.2019.04.003. Epub 2019 Apr 9. Mol Ther. 2019. PMID: 31023523 Free PMC article.
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