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The full spectrum of SLC22 OCT1 mutations illuminates the bridge between drug transporter biophysics and pharmacogenomics.
Yee SW, Macdonald CB, Mitrovic D, Zhou X, Koleske ML, Yang J, Buitrago Silva D, Rockefeller Grimes P, Trinidad DD, More SS, Kachuri L, Witte JS, Delemotte L, Giacomini KM, Coyote-Maestas W. Yee SW, et al. Among authors: zhou x. Mol Cell. 2024 May 16;84(10):1932-1947.e10. doi: 10.1016/j.molcel.2024.04.008. Epub 2024 May 3. Mol Cell. 2024. PMID: 38703769
The full spectrum of OCT1 (SLC22A1) mutations bridges transporter biophysics to drug pharmacogenomics.
Yee SW, Macdonald C, Mitrovic D, Zhou X, Koleske ML, Yang J, Silva DB, Grimes PR, Trinidad D, More SS, Kachuri L, Witte JS, Delemotte L, Giacomini KM, Coyote-Maestas W. Yee SW, et al. Among authors: zhou x. bioRxiv [Preprint]. 2023 Jun 7:2023.06.06.543963. doi: 10.1101/2023.06.06.543963. bioRxiv. 2023. PMID: 37333090 Free PMC article. Updated. Preprint.
Illuminating the Function of the Orphan Transporter, SLC22A10 in Humans and Other Primates.
Yee SW, Ferrández-Peral L, Alentorn P, Fontsere C, Ceylan M, Koleske ML, Handin N, Artegoitia VM, Lara G, Chien HC, Zhou X, Dainat J, Zalevsky A, Sali A, Brand CM, Capra JA, Artursson P, Newman JW, Marques-Bonet T, Giacomini KM. Yee SW, et al. Among authors: zhou x. bioRxiv [Preprint]. 2023 Aug 12:2023.08.08.552553. doi: 10.1101/2023.08.08.552553. bioRxiv. 2023. PMID: 37609337 Free PMC article. Updated. Preprint.
Illuminating the Function of the Orphan Transporter, SLC22A10 in Humans and Other Primates.
Yee SW, Ferrández-Peral L, Alentorn P, Fontsere C, Ceylan M, Koleske ML, Handin N, Artegoitia VM, Lara G, Chien HC, Zhou X, Dainat J, Zalevsky A, Sali A, Brand CM, Capra JA, Artursson P, Newman JW, Marques-Bonet T, Giacomini KM. Yee SW, et al. Among authors: zhou x. Res Sq [Preprint]. 2023 Sep 14:rs.3.rs-3263845. doi: 10.21203/rs.3.rs-3263845/v1. Res Sq. 2023. PMID: 37790518 Free PMC article. Updated. Preprint.
Illuminating the function of the orphan transporter, SLC22A10, in humans and other primates.
Yee SW, Ferrández-Peral L, Alentorn-Moron P, Fontsere C, Ceylan M, Koleske ML, Handin N, Artegoitia VM, Lara G, Chien HC, Zhou X, Dainat J, Zalevsky A, Sali A, Brand CM, Wolfreys FD, Yang J, Gestwicki JE, Capra JA, Artursson P, Newman JW, Marquès-Bonet T, Giacomini KM. Yee SW, et al. Among authors: zhou x. Nat Commun. 2024 May 23;15(1):4380. doi: 10.1038/s41467-024-48569-7. Nat Commun. 2024. PMID: 38782905 Free PMC article.
PharmVar GeneFocus: SLCO1B1.
Ramsey LB, Gong L, Lee SB, Wagner JB, Zhou X, Sangkuhl K, Adams SM, Straka RJ, Empey PE, Boone EC, Klein TE, Niemi M, Gaedigk A. Ramsey LB, et al. Among authors: zhou x. Clin Pharmacol Ther. 2023 Apr;113(4):782-793. doi: 10.1002/cpt.2705. Epub 2022 Jul 27. Clin Pharmacol Ther. 2023. PMID: 35797228 Free PMC article. Review.
Reply to Liu et al.: Tissue specificity of SIM1 gene expression and erectile dysfunction.
Jorgenson E, Matharu N, Palmer MR, Yin J, Shan J, Hoffmann TJ, Thai KK, Zhou X, Hotaling JM, Jarvik GP, Ahituv N, Wessells H, Van Den Eeden SK. Jorgenson E, et al. Among authors: zhou x. Proc Natl Acad Sci U S A. 2019 Feb 26;116(9):3349-3350. doi: 10.1073/pnas.1900162116. Epub 2019 Feb 12. Proc Natl Acad Sci U S A. 2019. PMID: 30755537 Free PMC article. No abstract available.
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