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Extreme elevations of donor-derived cell-free DNA increases the risk of chronic lung allograft dysfunction and death, even without clinical manifestations of disease.
Keller MB, Newman D, Alnababteh M, Ponor L, Shah P, Mathew J, Kong H, Andargie T, Park W, Charya A, Luikart H, Aryal S, Nathan SD, Orens JB, Khush KK, Jang M, Agbor-Enoh S. Keller MB, et al. Among authors: khush kk. J Heart Lung Transplant. 2024 May 3:S1053-2498(24)01644-9. doi: 10.1016/j.healun.2024.04.064. Online ahead of print. J Heart Lung Transplant. 2024. PMID: 38705500
Temporal response of the human virome to immunosuppression and antiviral therapy.
De Vlaminck I, Khush KK, Strehl C, Kohli B, Luikart H, Neff NF, Okamoto J, Snyder TM, Cornfield DN, Nicolls MR, Weill D, Bernstein D, Valantine HA, Quake SR. De Vlaminck I, et al. Among authors: khush kk. Cell. 2013 Nov 21;155(5):1178-87. doi: 10.1016/j.cell.2013.10.034. Cell. 2013. PMID: 24267896 Free PMC article.
Circulating cell-free DNA enables noninvasive diagnosis of heart transplant rejection.
De Vlaminck I, Valantine HA, Snyder TM, Strehl C, Cohen G, Luikart H, Neff NF, Okamoto J, Bernstein D, Weisshaar D, Quake SR, Khush KK. De Vlaminck I, et al. Among authors: khush kk. Sci Transl Med. 2014 Jun 18;6(241):241ra77. doi: 10.1126/scitranslmed.3007803. Sci Transl Med. 2014. PMID: 24944192 Free PMC article.
Noninvasive monitoring of infection and rejection after lung transplantation.
De Vlaminck I, Martin L, Kertesz M, Patel K, Kowarsky M, Strehl C, Cohen G, Luikart H, Neff NF, Okamoto J, Nicolls MR, Cornfield D, Weill D, Valantine H, Khush KK, Quake SR. De Vlaminck I, et al. Among authors: khush kk. Proc Natl Acad Sci U S A. 2015 Oct 27;112(43):13336-41. doi: 10.1073/pnas.1517494112. Epub 2015 Oct 12. Proc Natl Acad Sci U S A. 2015. PMID: 26460048 Free PMC article.
Monitoring pharmacologically induced immunosuppression by immune repertoire sequencing to detect acute allograft rejection in heart transplant patients: a proof-of-concept diagnostic accuracy study.
Vollmers C, De Vlaminck I, Valantine HA, Penland L, Luikart H, Strehl C, Cohen G, Khush KK, Quake SR. Vollmers C, et al. Among authors: khush kk. PLoS Med. 2015 Oct 14;12(10):e1001890. doi: 10.1371/journal.pmed.1001890. eCollection 2015 Oct. PLoS Med. 2015. PMID: 26466143 Free PMC article.
Paradoxical Vessel Remodeling of the Proximal Segment of the Left Anterior Descending Artery Predicts Long-Term Mortality After Heart Transplantation.
Okada K, Kitahara H, Yang HM, Tanaka S, Kobayashi Y, Kimura T, Luikart H, Yock PG, Yeung AC, Valantine HA, Fitzgerald PJ, Khush KK, Honda Y, Fearon WF. Okada K, et al. Among authors: khush kk. JACC Heart Fail. 2015 Dec;3(12):942-52. doi: 10.1016/j.jchf.2015.07.013. Epub 2015 Nov 11. JACC Heart Fail. 2015. PMID: 26577615 Free article.
Association of periarterial neovascularization with progression of cardiac allograft vasculopathy and long-term clinical outcomes in heart transplant recipients.
Kitahara H, Okada K, Tanaka S, Yang HM, Miki K, Kobayashi Y, Kimura T, Luikart H, Yock PG, Yeung AC, Fitzgerald PJ, Khush KK, Fearon WF, Honda Y. Kitahara H, et al. Among authors: khush kk. J Heart Lung Transplant. 2016 Jun;35(6):752-9. doi: 10.1016/j.healun.2016.02.002. Epub 2016 Mar 10. J Heart Lung Transplant. 2016. PMID: 27068036 Free PMC article.
188 results