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Extreme elevations of donor-derived cell-free DNA increases the risk of chronic lung allograft dysfunction and death, even without clinical manifestations of disease.
Keller MB, Newman D, Alnababteh M, Ponor L, Shah P, Mathew J, Kong H, Andargie T, Park W, Charya A, Luikart H, Aryal S, Nathan SD, Orens JB, Khush KK, Jang M, Agbor-Enoh S. Keller MB, et al. Among authors: luikart h. J Heart Lung Transplant. 2024 May 3:S1053-2498(24)01644-9. doi: 10.1016/j.healun.2024.04.064. Online ahead of print. J Heart Lung Transplant. 2024. PMID: 38705500
Late manifestation of alloantibody-associated injury and clinical pulmonary antibody-mediated rejection: Evidence from cell-free DNA analysis.
Agbor-Enoh S, Jackson AM, Tunc I, Berry GJ, Cochrane A, Grimm D, Davis A, Shah P, Brown AW, Wang Y, Timofte I, Shah P, Gorham S, Wylie J, Goodwin N, Jang MK, Marishta A, Bhatti K, Fideli U, Yang Y, Luikart H, Cao Z, Pirooznia M, Zhu J, Marboe C, Iacono A, Nathan SD, Orens J, Valantine HA, Khush K. Agbor-Enoh S, et al. Among authors: luikart h. J Heart Lung Transplant. 2018 Jul;37(7):925-932. doi: 10.1016/j.healun.2018.01.1305. Epub 2018 Jan 31. J Heart Lung Transplant. 2018. PMID: 29500138
Use of donor-derived-cell-free DNA as a marker of early allograft injury in primary graft dysfunction (PGD) to predict the risk of chronic lung allograft dysfunction (CLAD).
Keller M, Bush E, Diamond JM, Shah P, Matthew J, Brown AW, Sun J, Timofte I, Kong H, Tunc I, Luikart H, Iacono A, Nathan SD, Khush KK, Orens J, Jang M, Agbor-Enoh S. Keller M, et al. Among authors: luikart h. J Heart Lung Transplant. 2021 Jun;40(6):488-493. doi: 10.1016/j.healun.2021.02.008. Epub 2021 Feb 20. J Heart Lung Transplant. 2021. PMID: 33814284 Free PMC article.
Clinical features and allograft failure rates of pulmonary antibody-mediated rejection categories.
Charya AV, Ponor IL, Cochrane A, Levine D, Philogene M, Fu YP, Jang MK, Kong H, Shah P, Bon AM, Krishnan A, Mathew J, Luikart H, Khush KK, Berry G, Marboe C, Iacono A, Orens JB, Nathan SD, Agbor-Enoh S. Charya AV, et al. Among authors: luikart h. J Heart Lung Transplant. 2023 Feb;42(2):226-235. doi: 10.1016/j.healun.2022.09.012. Epub 2022 Sep 20. J Heart Lung Transplant. 2023. PMID: 36319530
Preemptive treatment of de novo donor-specific antibodies in lung transplant patients reduces subsequent risk of chronic lung allograft dysfunction or death.
Keller M, Yang S, Ponor L, Bon A, Cochrane A, Philogene M, Bush E, Shah P, Mathew J, Brown AW, Kong H, Charya A, Luikart H, Nathan SD, Khush KK, Jang M, Agbor-Enoh S. Keller M, et al. Among authors: luikart h. Am J Transplant. 2023 Apr;23(4):559-564. doi: 10.1016/j.ajt.2022.12.019. Epub 2023 Jan 19. Am J Transplant. 2023. PMID: 36732088 Free PMC article.
Association of periarterial neovascularization with progression of cardiac allograft vasculopathy and long-term clinical outcomes in heart transplant recipients.
Kitahara H, Okada K, Tanaka S, Yang HM, Miki K, Kobayashi Y, Kimura T, Luikart H, Yock PG, Yeung AC, Fitzgerald PJ, Khush KK, Fearon WF, Honda Y. Kitahara H, et al. Among authors: luikart h. J Heart Lung Transplant. 2016 Jun;35(6):752-9. doi: 10.1016/j.healun.2016.02.002. Epub 2016 Mar 10. J Heart Lung Transplant. 2016. PMID: 27068036 Free PMC article.
Applying rigor and reproducibility standards to assay donor-derived cell-free DNA as a non-invasive method for detection of acute rejection and graft injury after heart transplantation.
Agbor-Enoh S, Tunc I, De Vlaminck I, Fideli U, Davis A, Cuttin K, Bhatti K, Marishta A, Solomon MA, Jackson A, Graninger G, Harper B, Luikart H, Wylie J, Wang X, Berry G, Marboe C, Khush K, Zhu J, Valantine H. Agbor-Enoh S, et al. Among authors: luikart h. J Heart Lung Transplant. 2017 Sep;36(9):1004-1012. doi: 10.1016/j.healun.2017.05.026. Epub 2017 May 20. J Heart Lung Transplant. 2017. PMID: 28624139 Free PMC article.
Donor-derived cell-free DNA predicts allograft failure and mortality after lung transplantation.
Agbor-Enoh S, Wang Y, Tunc I, Jang MK, Davis A, De Vlaminck I, Luikart H, Shah PD, Timofte I, Brown AW, Marishta A, Bhatti K, Gorham S, Fideli U, Wylie J, Grimm D, Goodwin N, Yang Y, Patel K, Zhu J, Iacono A, Orens JB, Nathan SD, Marboe C, Berry GJ, Quake SR, Khush K, Valantine HA. Agbor-Enoh S, et al. Among authors: luikart h. EBioMedicine. 2019 Feb;40:541-553. doi: 10.1016/j.ebiom.2018.12.029. Epub 2019 Jan 26. EBioMedicine. 2019. PMID: 30692045 Free PMC article.
68 results