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Extreme elevations of donor-derived cell-free DNA increases the risk of chronic lung allograft dysfunction and death, even without clinical manifestations of disease.
Keller MB, Newman D, Alnababteh M, Ponor L, Shah P, Mathew J, Kong H, Andargie T, Park W, Charya A, Luikart H, Aryal S, Nathan SD, Orens JB, Khush KK, Jang M, Agbor-Enoh S. Keller MB, et al. Among authors: orens jb. J Heart Lung Transplant. 2024 May 3:S1053-2498(24)01644-9. doi: 10.1016/j.healun.2024.04.064. Online ahead of print. J Heart Lung Transplant. 2024. PMID: 38705500
Late manifestation of alloantibody-associated injury and clinical pulmonary antibody-mediated rejection: Evidence from cell-free DNA analysis.
Agbor-Enoh S, Jackson AM, Tunc I, Berry GJ, Cochrane A, Grimm D, Davis A, Shah P, Brown AW, Wang Y, Timofte I, Shah P, Gorham S, Wylie J, Goodwin N, Jang MK, Marishta A, Bhatti K, Fideli U, Yang Y, Luikart H, Cao Z, Pirooznia M, Zhu J, Marboe C, Iacono A, Nathan SD, Orens J, Valantine HA, Khush K. Agbor-Enoh S, et al. J Heart Lung Transplant. 2018 Jul;37(7):925-932. doi: 10.1016/j.healun.2018.01.1305. Epub 2018 Jan 31. J Heart Lung Transplant. 2018. PMID: 29500138
Use of donor-derived-cell-free DNA as a marker of early allograft injury in primary graft dysfunction (PGD) to predict the risk of chronic lung allograft dysfunction (CLAD).
Keller M, Bush E, Diamond JM, Shah P, Matthew J, Brown AW, Sun J, Timofte I, Kong H, Tunc I, Luikart H, Iacono A, Nathan SD, Khush KK, Orens J, Jang M, Agbor-Enoh S. Keller M, et al. J Heart Lung Transplant. 2021 Jun;40(6):488-493. doi: 10.1016/j.healun.2021.02.008. Epub 2021 Feb 20. J Heart Lung Transplant. 2021. PMID: 33814284 Free PMC article.
Donor-derived cell-free DNA accurately detects acute rejection in lung transplant patients, a multicenter cohort study.
Jang MK, Tunc I, Berry GJ, Marboe C, Kong H, Keller MB, Shah PD, Timofte I, Brown AW, Ponor IL, Mutebi C, Philogene MC, Yu K, Iacono A, Orens JB, Nathan SD, Agbor-Enoh S. Jang MK, et al. Among authors: orens jb. J Heart Lung Transplant. 2021 Aug;40(8):822-830. doi: 10.1016/j.healun.2021.04.009. Epub 2021 Apr 24. J Heart Lung Transplant. 2021. PMID: 34130911 Free PMC article.
Clinical features and allograft failure rates of pulmonary antibody-mediated rejection categories.
Charya AV, Ponor IL, Cochrane A, Levine D, Philogene M, Fu YP, Jang MK, Kong H, Shah P, Bon AM, Krishnan A, Mathew J, Luikart H, Khush KK, Berry G, Marboe C, Iacono A, Orens JB, Nathan SD, Agbor-Enoh S. Charya AV, et al. Among authors: orens jb. J Heart Lung Transplant. 2023 Feb;42(2):226-235. doi: 10.1016/j.healun.2022.09.012. Epub 2022 Sep 20. J Heart Lung Transplant. 2023. PMID: 36319530
Organizing pneumonia is associated with molecular allograft injury and the development of antibody-mediated rejection.
Keller MB, Tian X, Jang MK, Meda R, Charya A, Ozisik D, Berry GJ, Marboe CC, Kong H, Ponor IL, Aryal S, Orens JB, Shah PD, Nathan SD, Agbor-Enoh S. Keller MB, et al. Among authors: orens jb. J Heart Lung Transplant. 2024 Apr;43(4):563-570. doi: 10.1016/j.healun.2023.11.008. Epub 2023 Nov 14. J Heart Lung Transplant. 2024. PMID: 37972825
146 results