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A multimodal atlas of hepatocellular carcinoma reveals convergent evolutionary paths and 'bad apple' effect on clinical trajectory.
Chen J, Kaya NA, Zhang Y, Kendarsari RI, Sekar K, Lee Chong S, Seshachalam VP, Ling WH, Jin Phua CZ, Lai H, Yang H, Lu B, Lim JQ, Ma S, Chew SC, Chua KP, Alvarez JJS, Wu L, Ooi L, Chung AY, Cheow PC, Kam JH, Kow AW, Ganpathi IS, Bunchaliew C, Thammasiri J, Koh PS, Ong DB, Lim J, de Villa VH, Dela Cruz RD, Loh TJ, Wan WK, Leow WQ, Yang Y, Liu J, Skanderup AJ, Pang YH, Soon GST, Madhavan K, Lim TK, Bonney G, Goh BKP, Chew V, Dan YY, Toh HC, Foo RS, Tam WL, Zhai W, Chow PK. Chen J, et al. J Hepatol. 2024 May 21:S0168-8278(24)00352-0. doi: 10.1016/j.jhep.2024.05.017. Online ahead of print. J Hepatol. 2024. PMID: 38782118 Free article.
Multimodal molecular landscape of response to Y90-resin microsphere radioembolization followed by nivolumab for advanced hepatocellular carcinoma.
Kaya NA, Tai D, Lim X, Lim JQ, Lau MC, Goh D, Phua CZJ, Wee FYT, Joseph CR, Lim JCT, Neo ZW, Ye J, Cheung L, Lee J, Loke KSH, Gogna A, Yao F, Lee MY, Shuen TWH, Toh HC, Hilmer A, Chan YS, Lim TK, Tam WL, Choo SP, Yeong J, Zhai W. Kaya NA, et al. J Immunother Cancer. 2023 Aug;11(8):e007106. doi: 10.1136/jitc-2023-007106. J Immunother Cancer. 2023. PMID: 37586766 Free PMC article.
CD38 marks the exhausted CD8+ tissue-resident memory T cells in hepatocellular carcinoma.
Reolo MJY, Otsuka M, Seow JJW, Lee J, Lee YH, Nguyen PHD, Lim CJ, Wasser M, Chua C, Lim TKH, Leow WQ, Chung A, Goh BKP, Chow PKH, DasGupta R, Yeong JPS, Chew V. Reolo MJY, et al. Among authors: lim tkh. Front Immunol. 2023 Jun 12;14:1182016. doi: 10.3389/fimmu.2023.1182016. eCollection 2023. Front Immunol. 2023. PMID: 37377962 Free PMC article.
Immunohistochemical scoring of LAG-3 in conjunction with CD8 in the tumor microenvironment predicts response to immunotherapy in hepatocellular carcinoma.
Cheung CCL, Seah YHJ, Fang J, Orpilla NHC, Lau MC, Lim CJ, Lim X, Lee JNLW, Lim JCT, Lim S, Cheng Q, Toh HC, Choo SP, Lee SY, Lee JJX, Liu J, Lim TKH, Tai D, Yeong J. Cheung CCL, et al. Among authors: lim tkh. Front Immunol. 2023 Jun 5;14:1150985. doi: 10.3389/fimmu.2023.1150985. eCollection 2023. Front Immunol. 2023. PMID: 37342338 Free PMC article.
113 results