Parris KD - Search Results

1

Kinetics and mechanism of autoprocessing of human immunodeficiency virus type 1 protease from an analog of the Gag-Pol polyprotein.

Louis JM, Nashed NT, Parris KD, Kimmel AR, Jerina DM. Louis JM, et al. Among authors: parris kd. Proc Natl Acad Sci U S A. 1994 Aug 16;91(17):7970-4. doi: 10.1073/pnas.91.17.7970. Proc Natl Acad Sci U S A. 1994. PMID: 8058744 Free PMC article.

2

Synthesis and crystallographic analysis of two rhizopuspepsin inhibitor complexes.

Parris KD, Hoover DJ, Damon DB, Davies DR. Parris KD, et al. Biochemistry. 1992 Sep 8;31(35):8125-41. doi: 10.1021/bi00150a004. Biochemistry. 1992. PMID: 1525154

3

Structures of complexes of rhizopuspepsin with pepstatin and other statine-containing inhibitors.

Suguna K, Padlan EA, Bott R, Boger J, Parris KD, Davies DR. Suguna K, et al. Among authors: parris kd. Proteins. 1992 Jul;13(3):195-205. doi: 10.1002/prot.340130303. Proteins. 1992. PMID: 1603809

4

Crystal structures of rhizopuspepsin/inhibitor complexes.

Parris KD, Hoover DJ, Davies DR. Parris KD, et al. Adv Exp Med Biol. 1991;306:217-31. doi: 10.1007/978-1-4684-6012-4_26. Adv Exp Med Biol. 1991. PMID: 1812709 No abstract available.

5

Exchange of K+ or Cs+ for Na+ induces local and long-range changes in the three-dimensional structure of the tryptophan synthase alpha2beta2 complex.

Rhee S, Parris KD, Ahmed SA, Miles EW, Davies DR. Rhee S, et al. Among authors: parris kd. Biochemistry. 1996 Apr 2;35(13):4211-21. doi: 10.1021/bi952506d. Biochemistry. 1996. PMID: 8672457

6

Crystal structures of a mutant (betaK87T) tryptophan synthase alpha2beta2 complex with ligands bound to the active sites of the alpha- and beta-subunits reveal ligand-induced conformational changes.

Rhee S, Parris KD, Hyde CC, Ahmed SA, Miles EW, Davies DR. Rhee S, et al. Among authors: parris kd. Biochemistry. 1997 Jun 24;36(25):7664-80. doi: 10.1021/bi9700429. Biochemistry. 1997. PMID: 9201907

7

Ligand-mediated changes in the tryptophan synthase indole tunnel probed by nile red fluorescence with wild type, mutant, and chemically modified enzymes.

Ruvinov SB, Yang XJ, Parris KD, Banik U, Ahmed SA, Miles EW, Sackett DL. Ruvinov SB, et al. Among authors: parris kd. J Biol Chem. 1995 Mar 17;270(11):6357-69. doi: 10.1074/jbc.270.11.6357. J Biol Chem. 1995. PMID: 7890774 Free article.

8

Crystal structures of substrate binding to Bacillus subtilis holo-(acyl carrier protein) synthase reveal a novel trimeric arrangement of molecules resulting in three active sites.

Parris KD, Lin L, Tam A, Mathew R, Hixon J, Stahl M, Fritz CC, Seehra J, Somers WS. Parris KD, et al. Structure. 2000 Aug 15;8(8):883-95. doi: 10.1016/s0969-2126(00)00178-7. Structure. 2000. PMID: 10997907 Free article.

9

Catalytically active MAP KAP kinase 2 structures in complex with staurosporine and ADP reveal differences with the autoinhibited enzyme.

Underwood KW, Parris KD, Federico E, Mosyak L, Czerwinski RM, Shane T, Taylor M, Svenson K, Liu Y, Hsiao CL, Wolfrom S, Maguire M, Malakian K, Telliez JB, Lin LL, Kriz RW, Seehra J, Somers WS, Stahl ML. Underwood KW, et al. Among authors: parris kd. Structure. 2003 Jun;11(6):627-36. doi: 10.1016/s0969-2126(03)00092-3. Structure. 2003. PMID: 12791252 Free article.

10

Utilizing structures of CYP2D6 and BACE1 complexes to reduce risk of drug-drug interactions with a novel series of centrally efficacious BACE1 inhibitors.

Brodney MA, Beck EM, Butler CR, Barreiro G, Johnson EF, Riddell D, Parris K, Nolan CE, Fan Y, Atchison K, Gonzales C, Robshaw AE, Doran SD, Bundesmann MW, Buzon L, Dutra J, Henegar K, LaChapelle E, Hou X, Rogers BN, Pandit J, Lira R, Martinez-Alsina L, Mikochik P, Murray JC, Ogilvie K, Price L, Sakya SM, Yu A, Zhang Y, O'Neill BT. Brodney MA, et al. J Med Chem. 2015 Apr 9;58(7):3223-52. doi: 10.1021/acs.jmedchem.5b00191. Epub 2015 Apr 1. J Med Chem. 2015. PMID: 25781223 Free PMC article.

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