McCague R - Search Results

1

The importance of tamoxifen metabolism in tamoxifen-stimulated breast tumor growth.

Osborne CK, Jarman M, McCague R, Coronado EB, Hilsenbeck SG, Wakeling AE. Osborne CK, et al. Among authors: mccague r. Cancer Chemother Pharmacol. 1994;34(2):89-95. doi: 10.1007/BF00685924. Cancer Chemother Pharmacol. 1994. PMID: 8194171

2

Pyrrolidino-4-iodotamoxifen and 4-iodotamoxifen, new analogues of the antiestrogen tamoxifen for the treatment of breast cancer.

Chander SK, McCague R, Luqmani Y, Newton C, Dowsett M, Jarman M, Coombes RC. Chander SK, et al. Among authors: mccague r. Cancer Res. 1991 Nov 1;51(21):5851-8. Cancer Res. 1991. PMID: 1933854

3

Metabolism of tamoxifen by isolated rat hepatocytes. Identification of the glucuronide of 4-hydroxytamoxifen.

McCague R, Parr IB, Leclercq G, Leung OT, Jarman M. McCague R, et al. Biochem Pharmacol. 1990 May 1;39(9):1459-65. doi: 10.1016/0006-2952(90)90427-m. Biochem Pharmacol. 1990. PMID: 2334445

4

Comparison between inhibition of protein kinase C and antagonism of calmodulin by tamoxifen analogues.

Rowlands MG, Budworth J, Jarman M, Hardcastle IR, McCague R, Gescher A. Rowlands MG, et al. Among authors: mccague r. Biochem Pharmacol. 1995 Aug 25;50(5):723-6. doi: 10.1016/0006-2952(95)00186-4. Biochem Pharmacol. 1995. PMID: 7669076

5

Idoxifene: report of a phase I study in patients with metastatic breast cancer.

Coombes RC, Haynes BP, Dowsett M, Quigley M, English J, Judson IR, Griggs LJ, Potter GA, McCague R, Jarman M. Coombes RC, et al. Among authors: mccague r. Cancer Res. 1995 Mar 1;55(5):1070-4. Cancer Res. 1995. PMID: 7866990 Clinical Trial.

6

Analysis of phase I and phase II metabolites of tamoxifen in breast cancer patients.

Poon GK, Chui YC, McCague R, Lłnning PE, Feng R, Rowlands MG, Jarman M. Poon GK, et al. Among authors: mccague r. Drug Metab Dispos. 1993 Nov-Dec;21(6):1119-24. Drug Metab Dispos. 1993. PMID: 7905393

7

Variation of the inhibition of calmodulin dependent cyclic AMP phosphodiesterase amongst analogues of tamoxifen; correlations with cytotoxicity.

Rowlands MG, Parr IB, McCague R, Jarman M, Goddard PM. Rowlands MG, et al. Among authors: mccague r. Biochem Pharmacol. 1990 Jul 15;40(2):283-9. doi: 10.1016/0006-2952(90)90689-i. Biochem Pharmacol. 1990. PMID: 2165403

8

Derivatives of tamoxifen. Dependence of antiestrogenicity on the 4-substituent.

McCague R, Leclercq G, Legros N, Goodman J, Blackburn GM, Jarman M, Foster AB. McCague R, et al. J Med Chem. 1989 Dec;32(12):2527-33. doi: 10.1021/jm00132a006. J Med Chem. 1989. PMID: 2585441

9

Non-isomerisable antiestrogens related to tamoxifen.

McCague R, Jarman M, Leung OT, Foster AB, Leclercq G, Stoessel S. McCague R, et al. J Steroid Biochem. 1988 Oct;31(4B):545-7. doi: 10.1016/0022-4731(88)90005-2. J Steroid Biochem. 1988. PMID: 3199805

10

Hydroxy derivatives of tamoxifen.

Foster AB, Jarman M, Leung OT, McCague R, Leclercq G, Devleeschouwer N. Foster AB, et al. Among authors: mccague r. J Med Chem. 1985 Oct;28(10):1491-7. doi: 10.1021/jm00148a020. J Med Chem. 1985. PMID: 4045924

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