Champness JN - Search Results

1

Preliminary crystallographic data for Pneumocystis carinii dihydrofolate reductase.

Stammers DK, Delves C, Ballantine S, Jones EY, Stuart DI, Achari A, Bryant PK, Champness JN. Stammers DK, et al. Among authors: champness jn. J Mol Biol. 1993 Mar 20;230(2):679-80. doi: 10.1006/jmbi.1993.1183. J Mol Biol. 1993. PMID: 8464076

2

The structure of Pneumocystis carinii dihydrofolate reductase to 1.9 A resolution.

Champness JN, Achari A, Ballantine SP, Bryant PK, Delves CJ, Stammers DK. Champness JN, et al. Structure. 1994 Oct 15;2(10):915-24. doi: 10.1016/s0969-2126(94)00093-x. Structure. 1994. PMID: 7866743

3

Crystallographic investigation of the cooperative interaction between trimethoprim, reduced cofactor and dihydrofolate reductase.

Champness JN, Stammers DK, Beddell CR. Champness JN, et al. FEBS Lett. 1986 Apr 7;199(1):61-7. doi: 10.1016/0014-5793(86)81224-8. FEBS Lett. 1986. PMID: 3082676 Free article.

4

Crystal structure of the anti-bacterial sulfonamide drug target dihydropteroate synthase.

Achari A, Somers DO, Champness JN, Bryant PK, Rosemond J, Stammers DK. Achari A, et al. Among authors: champness jn. Nat Struct Biol. 1997 Jun;4(6):490-7. doi: 10.1038/nsb0697-490. Nat Struct Biol. 1997. PMID: 9187658

5

The structure of mouse L1210 dihydrofolate reductase-drug complexes and the construction of a model of human enzyme.

Stammers DK, Champness JN, Beddell CR, Dann JG, Eliopoulos E, Geddes AJ, Ogg D, North AC. Stammers DK, et al. Among authors: champness jn. FEBS Lett. 1987 Jun 22;218(1):178-84. doi: 10.1016/0014-5793(87)81042-6. FEBS Lett. 1987. PMID: 3595861 Free article.

6

Refined crystal structures of Escherichia coli and chicken liver dihydrofolate reductase containing bound trimethoprim.

Matthews DA, Bolin JT, Burridge JM, Filman DJ, Volz KW, Kaufman BT, Beddell CR, Champness JN, Stammers DK, Kraut J. Matthews DA, et al. Among authors: champness jn. J Biol Chem. 1985 Jan 10;260(1):381-91. J Biol Chem. 1985. PMID: 3880742 Free article.

7

Pyrrolo[2,3-d]pyrimidines and pyrido[2,3-d]pyrimidines as conformationally restricted analogues of the antibacterial agent trimethoprim.

Kuyper LF, Garvey JM, Baccanari DP, Champness JN, Stammers DK, Beddell CR. Kuyper LF, et al. Among authors: champness jn. Bioorg Med Chem. 1996 Apr;4(4):593-602. doi: 10.1016/0968-0896(96)00045-4. Bioorg Med Chem. 1996. PMID: 8735847

8

2.0 A X-ray structure of the ternary complex of 7,8-dihydro-6-hydroxymethylpterinpyrophosphokinase from Escherichia coli with ATP and a substrate analogue.

Stammers DK, Achari A, Somers DO, Bryant PK, Rosemond J, Scott DL, Champness JN. Stammers DK, et al. Among authors: champness jn. FEBS Lett. 1999 Jul 30;456(1):49-53. doi: 10.1016/s0014-5793(99)00860-1. FEBS Lett. 1999. PMID: 10452528 Free article.

9

The binding of trimethoprim to bacterial dihydrofolate reductase.

Baker DJ, Beddell CR, Champness JN, Goodford PJ, Norrington FE, Smith DR, Stammers DK. Baker DJ, et al. Among authors: champness jn. FEBS Lett. 1981 Apr 6;126(1):49-52. doi: 10.1016/0014-5793(81)81030-7. FEBS Lett. 1981. PMID: 7016582 Free article. No abstract available.

10

Receptor-based design of dihydrofolate reductase inhibitors: comparison of crystallographically determined enzyme binding with enzyme affinity in a series of carboxy-substituted trimethoprim analogues.

Kuyper LF, Roth B, Baccanari DP, Ferone R, Beddell CR, Champness JN, Stammers DK, Dann JG, Norrington FE, Baker DJ, et al. Kuyper LF, et al. Among authors: champness jn. J Med Chem. 1985 Mar;28(3):303-11. doi: 10.1021/jm00381a008. J Med Chem. 1985. PMID: 3973902

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

24 results

Search Page