Amyotrophic lateral sclerosis: the involvement of intracellular Ca2+ and protein kinase C.
Krieger C, Lanius RA, Pelech SL, Shaw CA.
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Trends Pharmacol Sci. 1996 Mar;17(3):114-20. doi: 10.1016/0165-6147(96)10004-3.
Trends Pharmacol Sci. 1996.
PMID: 8936348
Review.
Abnormalities in excitatory amino acids and their receptors, as well as disordered function of voltage-dependent Ca2+ channels and superoxide dismutase have been reported in ALS patients. Furthermore, the activity of protein kinase C (PKC), a Ca2+, phospholipid-dependent e …
Abnormalities in excitatory amino acids and their receptors, as well as disordered function of voltage-dependent Ca2+ channels and superoxid …