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A novel, picomolar inhibitor of human immunodeficiency virus type 1 protease.
Sham HL, Zhao C, Stewart KD, Betebenner DA, Lin S, Park CH, Kong XP, Rosenbrook W Jr, Herrin T, Madigan D, Vasavanonda S, Lyons N, Molla A, Saldivar A, Marsh KC, McDonald E, Wideburg NE, Denissen JF, Robins T, Kempf DJ, Plattner JJ, Norbeck DW. Sham HL, et al. Among authors: kempf dj. J Med Chem. 1996 Jan 19;39(2):392-7. doi: 10.1021/jm9507183. J Med Chem. 1996. PMID: 8558507
Inhibitors of HCV NS5B polymerase: synthesis and structure-activity relationships of N-1-heteroalkyl-4-hydroxyquinolon-3-yl-benzothiadiazines.
Pratt JK, Donner P, McDaniel KF, Maring CJ, Kati WM, Mo H, Middleton T, Liu Y, Ng T, Xie Q, Zhang R, Montgomery D, Molla A, Kempf DJ, Kohlbrenner W. Pratt JK, et al. Among authors: kempf dj. Bioorg Med Chem Lett. 2005 Mar 15;15(6):1577-82. doi: 10.1016/j.bmcl.2005.01.071. Bioorg Med Chem Lett. 2005. PMID: 15745800
Inhibitors of HCV NS5B polymerase: synthesis and structure-activity relationships of N-alkyl-4-hydroxyquinolon-3-yl-benzothiadiazine sulfamides.
Krueger AC, Madigan DL, Jiang WW, Kati WM, Liu D, Liu Y, Maring CJ, Masse S, McDaniel KF, Middleton T, Mo H, Molla A, Montgomery D, Pratt JK, Rockway TW, Zhang R, Kempf DJ. Krueger AC, et al. Among authors: kempf dj. Bioorg Med Chem Lett. 2006 Jul 1;16(13):3367-70. doi: 10.1016/j.bmcl.2006.04.015. Epub 2006 May 2. Bioorg Med Chem Lett. 2006. PMID: 16650764
Inhibitors of HCV NS5B polymerase: synthesis and structure-activity relationships of N-1-benzyl and N-1-[3-methylbutyl]-4-hydroxy-1,8-naphthyridon-3-yl benzothiadiazine analogs containing substituents on the aromatic ring.
Rockway TW, Zhang R, Liu D, Betebenner DA, McDaniel KF, Pratt JK, Beno D, Montgomery D, Jiang WW, Masse S, Kati WM, Middleton T, Molla A, Maring CJ, Kempf DJ. Rockway TW, et al. Among authors: kempf dj. Bioorg Med Chem Lett. 2006 Jul 15;16(14):3833-8. doi: 10.1016/j.bmcl.2006.04.022. Epub 2006 May 2. Bioorg Med Chem Lett. 2006. PMID: 16650984
Inhibitors of HCV NS5B polymerase: synthesis and structure-activity relationships of unsymmetrical 1-hydroxy-4,4-dialkyl-3-oxo-3,4-dihydronaphthalene benzothiadiazine derivatives.
Krueger AC, Madigan DL, Green BE, Hutchinson DK, Jiang WW, Kati WM, Liu Y, Maring CJ, Masse SV, McDaniel KF, Middleton TR, Mo H, Molla A, Montgomery DA, Ng TI, Kempf DJ. Krueger AC, et al. Among authors: kempf dj. Bioorg Med Chem Lett. 2007 Apr 15;17(8):2289-92. doi: 10.1016/j.bmcl.2007.01.072. Epub 2007 Jan 27. Bioorg Med Chem Lett. 2007. PMID: 17300933
140 results