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NMR-based discovery of lead inhibitors that block DNA binding of the human papillomavirus E2 protein.
J Med Chem. 1997 Sep 26;40(20):3144-50. doi: 10.1021/jm9703404.
J Med Chem. 1997.
PMID: 9379433
The discovery of furo[2,3-c]pyridine-based indanone oximes as potent and selective B-Raf inhibitors.
Buckmelter AJ, Ren L, Laird ER, Rast B, Miknis G, Wenglowsky S, Schlachter S, Welch M, Tarlton E, Grina J, Lyssikatos J, Brandhuber BJ, Morales T, Randolph N, Vigers G, Martinson M, Callejo M.
Buckmelter AJ, et al.
Bioorg Med Chem Lett. 2011 Feb 15;21(4):1248-52. doi: 10.1016/j.bmcl.2010.12.039. Epub 2010 Dec 10.
Bioorg Med Chem Lett. 2011.
PMID: 21211972
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Non-oxime inhibitors of B-Raf(V600E) kinase.
Ren L, Wenglowsky S, Miknis G, Rast B, Buckmelter AJ, Ely RJ, Schlachter S, Laird ER, Randolph N, Callejo M, Martinson M, Galbraith S, Brandhuber BJ, Vigers G, Morales T, Voegtli WC, Lyssikatos J.
Ren L, et al.
Bioorg Med Chem Lett. 2011 Feb 15;21(4):1243-7. doi: 10.1016/j.bmcl.2010.12.061. Epub 2010 Dec 19.
Bioorg Med Chem Lett. 2011.
PMID: 21251822
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Development of novel Asf1-H3/H4 inhibitors.
Miknis GF, Stevens SJ, Smith LE, Ostrov DA, Churchill ME.
Miknis GF, et al.
Bioorg Med Chem Lett. 2015 Feb 15;25(4):963-8. doi: 10.1016/j.bmcl.2014.11.067. Epub 2014 Dec 4.
Bioorg Med Chem Lett. 2015.
PMID: 25582598
Free PMC article.
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