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A novel, picomolar inhibitor of human immunodeficiency virus type 1 protease.
Sham HL, Zhao C, Stewart KD, Betebenner DA, Lin S, Park CH, Kong XP, Rosenbrook W Jr, Herrin T, Madigan D, Vasavanonda S, Lyons N, Molla A, Saldivar A, Marsh KC, McDonald E, Wideburg NE, Denissen JF, Robins T, Kempf DJ, Plattner JJ, Norbeck DW. Sham HL, et al. J Med Chem. 1996 Jan 19;39(2):392-7. doi: 10.1021/jm9507183. J Med Chem. 1996. PMID: 8558507
Potent inhibitors of the HIV-1 protease with good oral bioavailabilities.
Sham HL, Zhao C, Marsh KC, Betebenner DA, Lin S, McDonald E, Vasavanonda S, Wideburg N, Saldivar A, Robins T, et al. Sham HL, et al. Biochem Biophys Res Commun. 1995 Jun 6;211(1):159-65. doi: 10.1006/bbrc.1995.1791. Biochem Biophys Res Commun. 1995. PMID: 7779082
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