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2017 1
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2023 168
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473 results

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Page 1
APOE4 impairs the microglial response in Alzheimer's disease by inducing TGFβ-mediated checkpoints.
Yin Z, Rosenzweig N, Kleemann KL, Zhang X, Brandão W, Margeta MA, Schroeder C, Sivanathan KN, Silveira S, Gauthier C, Mallah D, Pitts KM, Durao A, Herron S, Shorey H, Cheng Y, Barry JL, Krishnan RK, Wakelin S, Rhee J, Yung A, Aronchik M, Wang C, Jain N, Bao X, Gerrits E, Brouwer N, Deik A, Tenen DG, Ikezu T, Santander NG, McKinsey GL, Baufeld C, Sheppard D, Krasemann S, Nowarski R, Eggen BJL, Clish C, Tanzi RE, Madore C, Arnold TD, Holtzman DM, Butovsky O. Yin Z, et al. Nat Immunol. 2023 Nov;24(11):1839-1853. doi: 10.1038/s41590-023-01627-6. Epub 2023 Sep 25. Nat Immunol. 2023. PMID: 37749326
APOE4 homozygozity represents a distinct genetic form of Alzheimer's disease.
Fortea J, Pegueroles J, Alcolea D, Belbin O, Dols-Icardo O, Vaqué-Alcázar L, Videla L, Gispert JD, Suárez-Calvet M, Johnson SC, Sperling R, Bejanin A, Lleó A, Montal V. Fortea J, et al. Nat Med. 2024 May;30(5):1284-1291. doi: 10.1038/s41591-024-02931-w. Epub 2024 May 6. Nat Med. 2024. PMID: 38710950
Association between APOE-ε4 allele and cognitive function is mediated by Alzheimer's disease pathology: a population-based autopsy study in an admixed sample.
Paradela RS, Justo AFO, Paes VR, Leite REP, Pasqualucci CA, Grinberg LT, Naslavsky MS, Zatz M, Nitrini R, Jacob-Filho W, Suemoto CK. Paradela RS, et al. Acta Neuropathol Commun. 2023 Dec 19;11(1):205. doi: 10.1186/s40478-023-01681-z. Acta Neuropathol Commun. 2023. PMID: 38115150 Free PMC article. Review.
A crosstalk between gut and brain in sepsis-induced cognitive decline.
Giridharan VV, Generoso JS, Lence L, Candiotto G, Streck E, Petronilho F, Pillai A, Sharshar T, Dal-Pizzol F, Barichello T. Giridharan VV, et al. J Neuroinflammation. 2022 May 23;19(1):114. doi: 10.1186/s12974-022-02472-4. J Neuroinflammation. 2022. PMID: 35606817 Free PMC article.
Gut microbiota-driven brain Aβ amyloidosis in mice requires microglia.
Dodiya HB, Lutz HL, Weigle IQ, Patel P, Michalkiewicz J, Roman-Santiago CJ, Zhang CM, Liang Y, Srinath A, Zhang X, Xia J, Olszewski M, Zhang X, Schipma MJ, Chang EB, Tanzi RE, Gilbert JA, Sisodia SS. Dodiya HB, et al. J Exp Med. 2022 Jan 3;219(1):e20200895. doi: 10.1084/jem.20200895. Epub 2021 Dec 2. J Exp Med. 2022. PMID: 34854884 Free PMC article.
473 results