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Genetic analysis of cancer drivers reveals cohesin and CTCF as suppressors of PD-L1.
Proc Natl Acad Sci U S A. 2022 Feb 15;119(7):e2120540119. doi: 10.1073/pnas.2120540119.
Proc Natl Acad Sci U S A. 2022.
PMID: 35149558
Free PMC article.
Splicing modulators impair DNA damage response and induce killing of cohesin-mutant MDS and AML.
Wheeler EC, Martin BJE, Doyle WC, Neaher S, Conway CA, Pitton CN, Gorelov RA, Donahue M, Jann JC, Abdel-Wahab O, Taylor J, Seiler M, Buonamici S, Pikman Y, Garcia JS, Belizaire R, Adelman K, Tothova Z.
Wheeler EC, et al.
Sci Transl Med. 2024 Jan 3;16(728):eade2774. doi: 10.1126/scitranslmed.ade2774. Epub 2024 Jan 3.
Sci Transl Med. 2024.
PMID: 38170787
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