GM62548/GM/NIGMS NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2001	1
2002	1
2003	2
2004	2
2005	4
2007	6
2008	1
2009	1
2010	1
2012	1
2024	0

1

The adenylyl cyclase activity of anthrax edema factor.

Tang WJ, Guo Q. Tang WJ, et al. Mol Aspects Med. 2009 Dec;30(6):423-30. doi: 10.1016/j.mam.2009.06.001. Epub 2009 Jun 26. Mol Aspects Med. 2009. PMID: 19560485 Free PMC article. Review.

2

Calcium-independent calmodulin binding and two-metal-ion catalytic mechanism of anthrax edema factor.

Shen Y, Zhukovskaya NL, Guo Q, Florián J, Tang WJ. Shen Y, et al. EMBO J. 2005 Mar 9;24(5):929-41. doi: 10.1038/sj.emboj.7600574. Epub 2005 Feb 17. EMBO J. 2005. PMID: 15719022 Free PMC article.

3

Physiological calcium concentrations regulate calmodulin binding and catalysis of adenylyl cyclase exotoxins.

Shen Y, Lee YS, Soelaiman S, Bergson P, Lu D, Chen A, Beckingham K, Grabarek Z, Mrksich M, Tang WJ. Shen Y, et al. EMBO J. 2002 Dec 16;21(24):6721-32. doi: 10.1093/emboj/cdf681. EMBO J. 2002. PMID: 12485993 Free PMC article.

4

Structure of anthrax edema factor-calmodulin-adenosine 5'-(alpha,beta-methylene)-triphosphate complex reveals an alternative mode of ATP binding to the catalytic site.

Shen Y, Guo Q, Zhukovskaya NL, Drum CL, Bohm A, Tang WJ. Shen Y, et al. Biochem Biophys Res Commun. 2004 Apr 30;317(2):309-14. doi: 10.1016/j.bbrc.2004.03.046. Biochem Biophys Res Commun. 2004. PMID: 15063758

5

Crystallization and preliminary X-ray study of the edema factor exotoxin adenylyl cyclase domain from Bacillus anthracis in the presence of its activator, calmodulin.

Drum CL, Shen Y, Rice PA, Bohm A, Tang WJ. Drum CL, et al. Acta Crystallogr D Biol Crystallogr. 2001 Dec;57(Pt 12):1881-4. doi: 10.1107/s0907444901014937. Epub 2001 Nov 21. Acta Crystallogr D Biol Crystallogr. 2001. PMID: 11717504

6

Antiinflammatory cAMP signaling and cell migration genes co-opted by the anthrax bacillus.

Kim C, Wilcox-Adelman S, Sano Y, Tang WJ, Collier RJ, Park JM. Kim C, et al. Proc Natl Acad Sci U S A. 2008 Apr 22;105(16):6150-5. doi: 10.1073/pnas.0800105105. Epub 2008 Apr 21. Proc Natl Acad Sci U S A. 2008. PMID: 18427110 Free PMC article.

7

Interactions of Bordetella pertussis adenylyl cyclase toxin CyaA with calmodulin mutants and calmodulin antagonists: comparison with membranous adenylyl cyclase I.

Schuler D, Lübker C, Lushington GH, Tang WJ, Shen Y, Richter M, Seifert R. Schuler D, et al. Biochem Pharmacol. 2012 Apr 1;83(7):839-848. doi: 10.1016/j.bcp.2012.01.005. Epub 2012 Jan 13. Biochem Pharmacol. 2012. PMID: 22265637 Free PMC article.

8

Insights from atomic-resolution X-ray structures of chemically synthesized HIV-1 protease in complex with inhibitors.

Johnson EC, Malito E, Shen Y, Pentelute B, Rich D, Florián J, Tang WJ, Kent SB. Johnson EC, et al. J Mol Biol. 2007 Oct 26;373(3):573-86. doi: 10.1016/j.jmb.2007.07.054. Epub 2007 Aug 2. J Mol Biol. 2007. PMID: 17869270 Free PMC article.

9

Bacillus anthracis edema toxin causes extensive tissue lesions and rapid lethality in mice.

Firoved AM, Miller GF, Moayeri M, Kakkar R, Shen Y, Wiggins JF, McNally EM, Tang WJ, Leppla SH. Firoved AM, et al. Am J Pathol. 2005 Nov;167(5):1309-20. doi: 10.1016/S0002-9440(10)61218-7. Am J Pathol. 2005. PMID: 16251415 Free PMC article.

10

Anthrax edema toxin sensitizes DBA/2J mice to lethal toxin.

Firoved AM, Moayeri M, Wiggins JF, Shen Y, Tang WJ, Leppla SH. Firoved AM, et al. Infect Immun. 2007 May;75(5):2120-5. doi: 10.1128/IAI.01781-06. Epub 2007 Mar 5. Infect Immun. 2007. PMID: 17339348 Free PMC article.

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