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Intra- and interchromosomal contact mapping reveals the Igh locus has extensive conformational heterogeneity and interacts with B-lineage genes.
Mielczarek O, Rogers CH, Zhan Y, Matheson LS, Stubbington MJT, Schoenfelder S, Bolland DJ, Javierre BM, Wingett SW, Várnai C, Segonds-Pichon A, Conn SJ, Krueger F, Andrews S, Fraser P, Giorgetti L, Corcoran AE. Mielczarek O, et al. Cell Rep. 2023 Sep 26;42(9):113074. doi: 10.1016/j.celrep.2023.113074. Epub 2023 Sep 6. Cell Rep. 2023. PMID: 37676766 Free PMC article.
Short- and long-range cis interactions between integrated HPV genomes and cellular chromatin dysregulate host gene expression in early cervical carcinogenesis.
Groves IJ, Drane ELA, Michalski M, Monahan JM, Scarpini CG, Smith SP, Bussotti G, Várnai C, Schoenfelder S, Fraser P, Enright AJ, Coleman N. Groves IJ, et al. PLoS Pathog. 2021 Aug 25;17(8):e1009875. doi: 10.1371/journal.ppat.1009875. eCollection 2021 Aug. PLoS Pathog. 2021. PMID: 34432858 Free PMC article.
Locus-specific induction of gene expression from heterochromatin loci during cellular senescence.
Tomimatsu K, Bihary D, Olan I, Parry AJ, Schoenfelder S, Chan ASL, Slater GSC, Ito Y, Rugg-Gunn PJ, Kirschner K, Bermejo-Rodriguez C, Seko T, Kugoh H, Shiraishi K, Sayama K, Kimura H, Fraser P, Narita M, Samarajiwa SA, Narita M. Tomimatsu K, et al. Nat Aging. 2022 Jan;2(1):31-45. doi: 10.1038/s43587-021-00147-y. Epub 2021 Dec 23. Nat Aging. 2022. PMID: 37118356
12 results