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Small-molecule inhibition and activation-loop trans-phosphorylation of the IGF1 receptor.
EMBO J. 2008 Jul 23;27(14):1985-94. doi: 10.1038/emboj.2008.116. Epub 2008 Jun 19.
EMBO J. 2008.
PMID: 18566589
Free PMC article.
Signaling properties of a non-metazoan Src kinase and the evolutionary history of Src negative regulation.
Li W, Young SL, King N, Miller WT.
Li W, et al.
J Biol Chem. 2008 May 30;283(22):15491-501. doi: 10.1074/jbc.M800002200. Epub 2008 Apr 4.
J Biol Chem. 2008.
PMID: 18390552
Free PMC article.
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The genome of the choanoflagellate Monosiga brevicollis and the origin of metazoans.
King N, Westbrook MJ, Young SL, Kuo A, Abedin M, Chapman J, Fairclough S, Hellsten U, Isogai Y, Letunic I, Marr M, Pincus D, Putnam N, Rokas A, Wright KJ, Zuzow R, Dirks W, Good M, Goodstein D, Lemons D, Li W, Lyons JB, Morris A, Nichols S, Richter DJ, Salamov A, Sequencing JG, Bork P, Lim WA, Manning G, Miller WT, McGinnis W, Shapiro H, Tjian R, Grigoriev IV, Rokhsar D.
King N, et al.
Nature. 2008 Feb 14;451(7180):783-8. doi: 10.1038/nature06617.
Nature. 2008.
PMID: 18273011
Free PMC article.
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The protist, Monosiga brevicollis, has a tyrosine kinase signaling network more elaborate and diverse than found in any known metazoan.
Manning G, Young SL, Miller WT, Zhai Y.
Manning G, et al.
Proc Natl Acad Sci U S A. 2008 Jul 15;105(28):9674-9. doi: 10.1073/pnas.0801314105. Epub 2008 Jul 10.
Proc Natl Acad Sci U S A. 2008.
PMID: 18621719
Free PMC article.
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