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MYC acetylated lysine residues drive oncogenic cell transformation and regulate select genetic programs for cell adhesion-independent growth and survival.
Hurd M, Pino J, Jang K, Allevato MM, Vorontchikhina M, Ichikawa W, Zhao Y, Gates R, Villalpando E, Hamilton MJ, Faiola F, Pan S, Qi Y, Hung YW, Girke T, Ann D, Seewaldt V, Martinez E. Hurd M, et al. Genes Dev. 2023 Oct 1;37(19-20):865-882. doi: 10.1101/gad.350736.123. Epub 2023 Oct 18. Genes Dev. 2023. PMID: 37852796 Free PMC article.
Inhibition of MYC by the SMARCB1 tumor suppressor.
Weissmiller AM, Wang J, Lorey SL, Howard GC, Martinez E, Liu Q, Tansey WP. Weissmiller AM, et al. Nat Commun. 2019 May 1;10(1):2014. doi: 10.1038/s41467-019-10022-5. Nat Commun. 2019. PMID: 31043611 Free PMC article.
BS69/ZMYND11 C-Terminal Domains Bind and Inhibit EBNA2.
Harter MR, Liu CD, Shen CL, Gonzalez-Hurtado E, Zhang ZM, Xu M, Martinez E, Peng CW, Song J. Harter MR, et al. PLoS Pathog. 2016 Feb 4;12(2):e1005414. doi: 10.1371/journal.ppat.1005414. eCollection 2016 Feb. PLoS Pathog. 2016. PMID: 26845565 Free PMC article.
The interplay of long non-coding RNAs and MYC in cancer.
Hamilton MJ, Young MD, Sauer S, Martinez E. Hamilton MJ, et al. AIMS Biophys. 2015;2(4):794-809. doi: 10.3934/biophy.2015.4.794. Epub 2015 Dec 1. AIMS Biophys. 2015. PMID: 27077133 Free PMC article.
The human T-cell leukemia virus type-1 p30II protein activates p53 and induces the TIGAR and suppresses oncogene-induced oxidative stress during viral carcinogenesis.
Romeo M, Hutchison T, Malu A, White A, Kim J, Gardner R, Smith K, Nelson K, Bergeson R, McKee R, Harrod C, Ratner L, Lüscher B, Martinez E, Harrod R. Romeo M, et al. Virology. 2018 May;518:103-115. doi: 10.1016/j.virol.2018.02.010. Epub 2018 Feb 20. Virology. 2018. PMID: 29462755 Free PMC article.