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PD-L1-mediated gasdermin C expression switches apoptosis to pyroptosis in cancer cells and facilitates tumour necrosis.
Hou J, Zhao R, Xia W, Chang CW, You Y, Hsu JM, Nie L, Chen Y, Wang YC, Liu C, Wang WJ, Wu Y, Ke B, Hsu JL, Huang K, Ye Z, Yang Y, Xia X, Li Y, Li CW, Shao B, Tainer JA, Hung MC. Hou J, et al. Nat Cell Biol. 2020 Oct;22(10):1264-1275. doi: 10.1038/s41556-020-0575-z. Epub 2020 Sep 14. Nat Cell Biol. 2020. PMID: 32929201 Free PMC article.
RAD51C-XRCC3 structure and cancer patient mutations define DNA replication roles.
Longo MA, Roy S, Chen Y, Tomaszowski KH, Arvai AS, Pepper JT, Boisvert RA, Kunnimalaiyaan S, Keshvani C, Schild D, Bacolla A, Williams GJ, Tainer JA, Schlacher K. Longo MA, et al. Nat Commun. 2023 Jul 24;14(1):4445. doi: 10.1038/s41467-023-40096-1. Nat Commun. 2023. PMID: 37488098 Free PMC article.
Applying HT-SAXS to chemical ligand screening.
Brosey CA, Shen R, Moiani D, Jones DE, Burnett K, Hura GL, Tainer JA. Brosey CA, et al. Methods Enzymol. 2023;678:331-350. doi: 10.1016/bs.mie.2022.09.022. Epub 2022 Nov 26. Methods Enzymol. 2023. PMID: 36641213
Autism-Associated Vigilin Depletion Impairs DNA Damage Repair.
Banday S, Pandita RK, Mushtaq A, Bacolla A, Mir US, Singh DK, Jan S, Bhat KP, Hunt CR, Rao G, Charaka VK, Tainer JA, Pandita TK, Altaf M. Banday S, et al. Mol Cell Biol. 2021 Jun 23;41(7):e0008221. doi: 10.1128/MCB.00082-21. Epub 2021 Jun 23. Mol Cell Biol. 2021. PMID: 33941620 Free PMC article.
48 results