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Interferon-dependent signaling is critical for viral clearance in airway neutrophils.
Margaroli C, Fram T, Sharma NS, Patel SB, Tipper J, Robison SW, Russell DW, Fortmann SD, Banday MM, Soto-Vazquez Y, Abdalla T, Saitornuang S, Madison MC, Leal SM Jr, Harrod KS, Erdmann NB, Gaggar A. Margaroli C, et al. JCI Insight. 2023 May 22;8(10):e167042. doi: 10.1172/jci.insight.167042. JCI Insight. 2023. PMID: 37071484 Free PMC article.
A single intranasal administration of AdCOVID protects against SARS-CoV-2 infection in the upper and lower respiratory tracts.
Schultz MD, Suschak JJ, Botta D, Silva-Sanchez A, King RG, Detchemendy TW, Meshram CD, Foote JB, Zhou F, Tipper JL, Zhang J, Harrod KS, Leal SM Jr, Randall TD, Roberts MS, Georges B, Lund FE. Schultz MD, et al. Hum Vaccin Immunother. 2022 Nov 30;18(6):2127292. doi: 10.1080/21645515.2022.2127292. Epub 2022 Oct 4. Hum Vaccin Immunother. 2022. PMID: 36194255 Free PMC article.
Mucociliary transport deficiency and disease progression in Syrian hamsters with SARS-CoV-2 infection.
Li Q, Vijaykumar K, Phillips SE, Hussain SS, Huynh NV, Fernandez-Petty CM, Lever JEP, Foote JB, Ren J, Campos-Gómez J, Daya FA, Hubbs NW, Kim H, Onuoha E, Boitet ER, Fu L, Leung HM, Yu L, Detchemendy TW, Schaefers LT, Tipper JL, Edwards LJ, Leal SM Jr, Harrod KS, Tearney GJ, Rowe SM. Li Q, et al. JCI Insight. 2023 Jan 10;8(1):e163962. doi: 10.1172/jci.insight.163962. JCI Insight. 2023. PMID: 36625345 Free PMC article.