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Dynamic chromatin accessibility licenses STAT5- and STAT6-dependent innate-like function of TH9 cells to promote allergic inflammation.
Son A, Meylan F, Gomez-Rodriguez J, Kaul Z, Sylvester M, Falduto GH, Vazquez E, Haque T, Kitakule MM, Wang C, Manthiram K, Qi CF, Cheng J, Gurram RK, Zhu J, Schwartzberg P, Milner JD, Frischmeyer-Guerrerio PA, Schwartz DM. Son A, et al. Nat Immunol. 2023 Jun;24(6):1036-1048. doi: 10.1038/s41590-023-01501-5. Epub 2023 Apr 27. Nat Immunol. 2023. PMID: 37106040 Free PMC article.
Persistent tryptase elevation in a patient with Gaucher disease.
Schussler E, Yang A, Lyons JJ, Milner JD, Wang J. Schussler E, et al. J Allergy Clin Immunol Pract. 2018 Mar-Apr;6(2):697-699. doi: 10.1016/j.jaip.2017.08.039. Epub 2017 Oct 13. J Allergy Clin Immunol Pract. 2018. PMID: 29033258 Free PMC article. No abstract available.
Loss of the interleukin-6 receptor causes immunodeficiency, atopy, and abnormal inflammatory responses.
Spencer S, Köstel Bal S, Egner W, Lango Allen H, Raza SI, Ma CA, Gürel M, Zhang Y, Sun G, Sabroe RA, Greene D, Rae W, Shahin T, Kania K, Ardy RC, Thian M, Staples E, Pecchia-Bekkum A, Worrall WPM, Stephens J, Brown M, Tuna S, York M, Shackley F, Kerrin D, Sargur R, Condliffe A, Tipu HN, Kuehn HS, Rosenzweig SD, Turro E, Tavaré S, Thrasher AJ, Jodrell DI, Smith KGC, Boztug K, Milner JD, Thaventhiran JED. Spencer S, et al. J Exp Med. 2019 Sep 2;216(9):1986-1998. doi: 10.1084/jem.20190344. Epub 2019 Jun 24. J Exp Med. 2019. PMID: 31235509 Free PMC article.