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Opposing activities of oncogenic MIR17HG and tumor suppressive MIR100HG clusters and their gene targets regulate replicative senescence in human adult stem cells.
Lopez MF, Niu P, Wang L, Vogelsang M, Gaur M, Krastins B, Zhao Y, Smagul A, Nussupbekova A, Akanov AA, Jordan IK, Lunyak VV. Lopez MF, et al. Among authors: akanov aa. NPJ Aging Mech Dis. 2017 Apr 20;3:7. doi: 10.1038/s41514-017-0006-y. eCollection 2017. NPJ Aging Mech Dis. 2017. PMID: 28649425 Free PMC article.
Transcriptional profiling of interleukin-2-primed human adipose derived mesenchymal stem cells revealed dramatic changes in stem cells response imposed by replicative senescence.
Niu P, Smagul A, Wang L, Sadvakas A, Sha Y, Pérez LM, Nussupbekova A, Amirbekov A, Akanov AA, Gálvez BG, Jordan IK, Lunyak VV. Niu P, et al. Among authors: akanov aa. Oncotarget. 2015 Jul 20;6(20):17938-57. doi: 10.18632/oncotarget.4852. Oncotarget. 2015. PMID: 26255627 Free PMC article.
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