Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

80 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Results By Year timeline is not available.
Page 1
Inhibition of HIV Maturation via Selective Unfolding and Cross-Linking of Gag Polyprotein by a Mercaptobenzamide Acetylator.
Miller Jenkins LM, Paine EL, Deshmukh L, Nikolayevskiy H, Lyons GC, Scerba MT, George Rosenker K, Luecke HF, Louis JM, Chertova E, Gorelick RJ, Ott DE, Clore GM, Appella DH. Miller Jenkins LM, et al. Among authors: appella dh. J Am Chem Soc. 2019 May 22;141(20):8327-8338. doi: 10.1021/jacs.9b02743. Epub 2019 May 13. J Am Chem Soc. 2019. PMID: 31042030 Free PMC article.
Small-molecule inactivation of HIV-1 NCp7 by repetitive intracellular acyl transfer.
Miller Jenkins LM, Ott DE, Hayashi R, Coren LV, Wang D, Xu Q, Schito ML, Inman JK, Appella DH, Appella E. Miller Jenkins LM, et al. Among authors: appella dh, appella e. Nat Chem Biol. 2010 Dec;6(12):887-9. doi: 10.1038/nchembio.456. Epub 2010 Oct 17. Nat Chem Biol. 2010. PMID: 20953192 Free PMC article.
PNA-Based Multivalent Scaffolds Activate the Dopamine D2 Receptor.
Dix AV, Conroy JL, George Rosenker KM, Sibley DR, Appella DH. Dix AV, et al. Among authors: appella dh. ACS Med Chem Lett. 2015 Mar 13;6(4):425-9. doi: 10.1021/ml500478m. eCollection 2015 Apr 9. ACS Med Chem Lett. 2015. PMID: 25893044 Free PMC article.
Preclinical evaluation of a mercaptobenzamide and its prodrug for NCp7-targeted inhibition of human immunodeficiency virus.
Hartman TL, Yang L, Helfrick AN, Hassink M, Shank NI, George Rosenker K, Scerba MT, Saha M, Hughes E, Wang AQ, Xu X, Gupta P, Buckheit RW Jr, Appella DH. Hartman TL, et al. Among authors: appella dh. Antiviral Res. 2016 Oct;134:216-225. doi: 10.1016/j.antiviral.2016.08.022. Epub 2016 Aug 26. Antiviral Res. 2016. PMID: 27568924 Free PMC article.
Probing Mercaptobenzamides as HIV Inactivators via Nucleocapsid Protein 7.
Saha M, Scerba MT, Shank NI, Hartman TL, Buchholz CA, Buckheit RW Jr, Durell SR, Appella DH. Saha M, et al. Among authors: appella dh. ChemMedChem. 2017 May 22;12(10):714-721. doi: 10.1002/cmdc.201700141. Epub 2017 Apr 25. ChemMedChem. 2017. PMID: 28395128 Free PMC article.
Synthesis and Application of LKγT Peptide Nucleic Acids.
Shank N, George Rosenker KM, Englund EA, Dix AV, Rastede EE, Appella DH. Shank N, et al. Among authors: appella dh. Methods Mol Biol. 2019;1973:131-145. doi: 10.1007/978-1-4939-9216-4_8. Methods Mol Biol. 2019. PMID: 31016699
The structure-activity profile of mercaptobenzamides' anti-HIV activity suggests that thermodynamics of metabolism is more important than binding affinity to the target.
Nikolayevskiy H, Robello M, Scerba MT, Pasternak EH, Saha M, Hartman TL, Buchholz CA, Buckheit RW Jr, Durell SR, Appella DH. Nikolayevskiy H, et al. Among authors: appella dh. Eur J Med Chem. 2019 Sep 15;178:818-837. doi: 10.1016/j.ejmech.2019.06.020. Epub 2019 Jun 9. Eur J Med Chem. 2019. PMID: 31252286 Free PMC article.
80 results