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HIV immune complexes prevent excitotoxicity by interaction with NMDA receptors.
Rumbaugh JA, Bachani M, Li W, Butler TR, Smith KJ, Bianchet MA, Wang T, Prendergast MA, Sacktor N, Nath A. Rumbaugh JA, et al. Among authors: bachani m. Neurobiol Dis. 2013 Jan;49:169-76. doi: 10.1016/j.nbd.2012.08.013. Epub 2012 Aug 25. Neurobiol Dis. 2013. PMID: 22940423 Free PMC article.
Chronic neuronal activation leads to elevated lactate dehydrogenase A through the AMP-activated protein kinase/hypoxia-inducible factor-1α hypoxia pathway.
Ksendzovsky A, Bachani M, Altshuler M, Walbridge S, Mortazavi A, Moyer M, Chen C, Fayed I, Steiner J, Edwards N, Inati SK, Jahanipour J, Maric D, Heiss JD, Kapur J, Zaghloul KA. Ksendzovsky A, et al. Among authors: bachani m. Brain Commun. 2022 Dec 1;5(1):fcac298. doi: 10.1093/braincomms/fcac298. eCollection 2023. Brain Commun. 2022. PMID: 36655171 Free PMC article.
Neurotoxic properties of the Zika virus envelope protein.
Steiner JP, Bachani M, Malik N, Li W, Tyagi R, Sampson K, Abrams RPM, Kousa Y, Solis J, Johnson TP, Nath A. Steiner JP, et al. Among authors: bachani m. Exp Neurol. 2023 Sep;367:114469. doi: 10.1016/j.expneurol.2023.114469. Epub 2023 Jun 14. Exp Neurol. 2023. PMID: 37327963
TDP-43 proteinopathy in ALS is triggered by loss of ASRGL1 and associated with HML-2 expression.
Garcia-Montojo M, Fathi S, Rastegar C, Simula ER, Doucet-O'Hare T, Cheng YHH, Abrams RPM, Pasternack N, Malik N, Bachani M, Disanza B, Maric D, Lee MH, Wang H, Santamaria U, Li W, Sampson K, Lorenzo JR, Sanchez IE, Mezghrani A, Li Y, Sechi LA, Pineda S, Heiman M, Kellis M, Steiner J, Nath A. Garcia-Montojo M, et al. Among authors: bachani m. Nat Commun. 2024 May 16;15(1):4163. doi: 10.1038/s41467-024-48488-7. Nat Commun. 2024. PMID: 38755145 Free PMC article.
30 results