Beusch I - Search Results

1

A transient α-helix in the N-terminal RNA recognition motif of polypyrimidine tract binding protein senses RNA secondary structure.

Maris C, Jayne S, Damberger FF, Beusch I, Dorn G, Ravindranathan S, Allain FH. Maris C, et al. Among authors: beusch i. Nucleic Acids Res. 2020 May 7;48(8):4521-4537. doi: 10.1093/nar/gkaa155. Nucleic Acids Res. 2020. PMID: 32170319 Free PMC article.

2

Tandem hnRNP A1 RNA recognition motifs act in concert to repress the splicing of survival motor neuron exon 7.

Beusch I, Barraud P, Moursy A, Cléry A, Allain FH. Beusch I, et al. Elife. 2017 Jun 26;6:e25736. doi: 10.7554/eLife.25736. Elife. 2017. PMID: 28650318 Free PMC article.

3

Targeted high-throughput mutagenesis of the human spliceosome reveals its in vivo operating principles.

Beusch I, Rao B, Studer MK, Luhovska T, Šukytė V, Lei S, Oses-Prieto J, SeGraves E, Burlingame A, Jonas S, Madhani HD. Beusch I, et al. Mol Cell. 2023 Jul 20;83(14):2578-2594.e9. doi: 10.1016/j.molcel.2023.06.003. Epub 2023 Jul 3. Mol Cell. 2023. PMID: 37402368

4

Coupling of spliceosome complexity to intron diversity.

Sales-Lee J, Perry DS, Bowser BA, Diedrich JK, Rao B, Beusch I, Yates JR 3rd, Roy SW, Madhani HD. Sales-Lee J, et al. Among authors: beusch i. Curr Biol. 2021 Nov 22;31(22):4898-4910.e4. doi: 10.1016/j.cub.2021.09.004. Epub 2021 Sep 22. Curr Biol. 2021. PMID: 34555349 Free PMC article.

5

Understanding the dynamic design of the spliceosome.

Beusch I, Madhani HD. Beusch I, et al. Trends Biochem Sci. 2024 Apr 18:S0968-0004(24)00078-1. doi: 10.1016/j.tibs.2024.03.012. Online ahead of print. Trends Biochem Sci. 2024. PMID: 38641465 Review.

6

RNA recognition by Npl3p reveals U2 snRNA-binding compatible with a chaperone role during splicing.

Moursy A, Cléry A, Gerhardy S, Betz KM, Rao S, Mazur J, Campagne S, Beusch I, Duszczyk MM, Robinson MD, Panse VG, Allain FH. Moursy A, et al. Among authors: beusch i. Nat Commun. 2023 Nov 7;14(1):7166. doi: 10.1038/s41467-023-42962-4. Nat Commun. 2023. PMID: 37935663 Free PMC article.

7

Meet the authors: Irene Beusch and Hiten Madhani.

Beusch I, Madhani H. Beusch I, et al. Mol Cell. 2023 Jul 20;83(14):2387-2389. doi: 10.1016/j.molcel.2023.06.030. Mol Cell. 2023. PMID: 37478821

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