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Page 1
Mechanism of voltage gating in potassium channels.
Jensen MØ, Jogini V, Borhani DW, Leffler AE, Dror RO, Shaw DE. Jensen MØ, et al. Among authors: borhani dw. Science. 2012 Apr 13;336(6078):229-33. doi: 10.1126/science.1216533. Science. 2012. PMID: 22499946
Principles of conduction and hydrophobic gating in K+ channels.
Jensen MØ, Borhani DW, Lindorff-Larsen K, Maragakis P, Jogini V, Eastwood MP, Dror RO, Shaw DE. Jensen MØ, et al. Among authors: borhani dw. Proc Natl Acad Sci U S A. 2010 Mar 30;107(13):5833-8. doi: 10.1073/pnas.0911691107. Epub 2010 Mar 15. Proc Natl Acad Sci U S A. 2010. PMID: 20231479 Free PMC article.
Pathway and mechanism of drug binding to G-protein-coupled receptors.
Dror RO, Pan AC, Arlow DH, Borhani DW, Maragakis P, Shan Y, Xu H, Shaw DE. Dror RO, et al. Among authors: borhani dw. Proc Natl Acad Sci U S A. 2011 Aug 9;108(32):13118-23. doi: 10.1073/pnas.1104614108. Epub 2011 Jul 21. Proc Natl Acad Sci U S A. 2011. PMID: 21778406 Free PMC article.
Activation mechanism of the β2-adrenergic receptor.
Dror RO, Arlow DH, Maragakis P, Mildorf TJ, Pan AC, Xu H, Borhani DW, Shaw DE. Dror RO, et al. Among authors: borhani dw. Proc Natl Acad Sci U S A. 2011 Nov 15;108(46):18684-9. doi: 10.1073/pnas.1110499108. Epub 2011 Oct 26. Proc Natl Acad Sci U S A. 2011. PMID: 22031696 Free PMC article.
Molecular determinants of drug-receptor binding kinetics.
Pan AC, Borhani DW, Dror RO, Shaw DE. Pan AC, et al. Among authors: borhani dw. Drug Discov Today. 2013 Jul;18(13-14):667-73. doi: 10.1016/j.drudis.2013.02.007. Epub 2013 Feb 27. Drug Discov Today. 2013. PMID: 23454741 Review.
Structural basis for modulation of a G-protein-coupled receptor by allosteric drugs.
Dror RO, Green HF, Valant C, Borhani DW, Valcourt JR, Pan AC, Arlow DH, Canals M, Lane JR, Rahmani R, Baell JB, Sexton PM, Christopoulos A, Shaw DE. Dror RO, et al. Among authors: borhani dw. Nature. 2013 Nov 14;503(7475):295-9. doi: 10.1038/nature12595. Epub 2013 Oct 13. Nature. 2013. PMID: 24121438
45 results