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CRISPR off-target detection with DISCOVER-seq.
Wienert B, Wyman SK, Yeh CD, Conklin BR, Corn JE. Wienert B, et al. Among authors: corn je. Nat Protoc. 2020 May;15(5):1775-1799. doi: 10.1038/s41596-020-0309-5. Epub 2020 Apr 20. Nat Protoc. 2020. PMID: 32313254 Free PMC article.
CRISPR germline engineering--the community speaks.
Bosley KS, Botchan M, Bredenoord AL, Carroll D, Charo RA, Charpentier E, Cohen R, Corn J, Doudna J, Feng G, Greely HT, Isasi R, Ji W, Kim JS, Knoppers B, Lanphier E, Li J, Lovell-Badge R, Martin GS, Moreno J, Naldini L, Pera M, Perry AC, Venter JC, Zhang F, Zhou Q. Bosley KS, et al. Nat Biotechnol. 2015 May;33(5):478-86. doi: 10.1038/nbt.3227. Nat Biotechnol. 2015. PMID: 25965754 No abstract available.
Co-opting CRISPR to deliver functional RNAs.
Lin PC, Corn JE. Lin PC, et al. Among authors: corn je. Nat Methods. 2015 Jul;12(7):613-4. doi: 10.1038/nmeth.3452. Nat Methods. 2015. PMID: 26125593 No abstract available.
Cornerstones of CRISPR-Cas in drug discovery and therapy.
Fellmann C, Gowen BG, Lin PC, Doudna JA, Corn JE. Fellmann C, et al. Among authors: corn je. Nat Rev Drug Discov. 2017 Feb;16(2):89-100. doi: 10.1038/nrd.2016.238. Epub 2016 Dec 23. Nat Rev Drug Discov. 2017. PMID: 28008168 Free PMC article. Review.
Disabling Cas9 by an anti-CRISPR DNA mimic.
Shin J, Jiang F, Liu JJ, Bray NL, Rauch BJ, Baik SH, Nogales E, Bondy-Denomy J, Corn JE, Doudna JA. Shin J, et al. Among authors: corn je. Sci Adv. 2017 Jul 12;3(7):e1701620. doi: 10.1126/sciadv.1701620. eCollection 2017 Jul. Sci Adv. 2017. PMID: 28706995 Free PMC article.
Discovery of stimulation-responsive immune enhancers with CRISPR activation.
Simeonov DR, Gowen BG, Boontanrart M, Roth TL, Gagnon JD, Mumbach MR, Satpathy AT, Lee Y, Bray NL, Chan AY, Lituiev DS, Nguyen ML, Gate RE, Subramaniam M, Li Z, Woo JM, Mitros T, Ray GJ, Curie GL, Naddaf N, Chu JS, Ma H, Boyer E, Van Gool F, Huang H, Liu R, Tobin VR, Schumann K, Daly MJ, Farh KK, Ansel KM, Ye CJ, Greenleaf WJ, Anderson MS, Bluestone JA, Chang HY, Corn JE, Marson A. Simeonov DR, et al. Among authors: corn je. Nature. 2017 Sep 7;549(7670):111-115. doi: 10.1038/nature23875. Epub 2017 Aug 30. Nature. 2017. PMID: 28854172 Free PMC article.
Enhancer connectome in primary human cells identifies target genes of disease-associated DNA elements.
Mumbach MR, Satpathy AT, Boyle EA, Dai C, Gowen BG, Cho SW, Nguyen ML, Rubin AJ, Granja JM, Kazane KR, Wei Y, Nguyen T, Greenside PG, Corces MR, Tycko J, Simeonov DR, Suliman N, Li R, Xu J, Flynn RA, Kundaje A, Khavari PA, Marson A, Corn JE, Quertermous T, Greenleaf WJ, Chang HY. Mumbach MR, et al. Among authors: corn je. Nat Genet. 2017 Nov;49(11):1602-1612. doi: 10.1038/ng.3963. Epub 2017 Sep 25. Nat Genet. 2017. PMID: 28945252 Free PMC article.
89 results