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An anti-diabetes agent protects the mouse brain from defective insulin signaling caused by Alzheimer's disease- associated Aβ oligomers.
Bomfim TR, Forny-Germano L, Sathler LB, Brito-Moreira J, Houzel JC, Decker H, Silverman MA, Kazi H, Melo HM, McClean PL, Holscher C, Arnold SE, Talbot K, Klein WL, Munoz DP, Ferreira ST, De Felice FG. Bomfim TR, et al. Among authors: ferreira st. J Clin Invest. 2012 Apr;122(4):1339-53. doi: 10.1172/JCI57256. J Clin Invest. 2012. PMID: 22476196 Free PMC article.
Memantine rescues transient cognitive impairment caused by high-molecular-weight aβ oligomers but not the persistent impairment induced by low-molecular-weight oligomers.
Figueiredo CP, Clarke JR, Ledo JH, Ribeiro FC, Costa CV, Melo HM, Mota-Sales AP, Saraiva LM, Klein WL, Sebollela A, De Felice FG, Ferreira ST. Figueiredo CP, et al. Among authors: ferreira st. J Neurosci. 2013 Jun 5;33(23):9626-34. doi: 10.1523/JNEUROSCI.0482-13.2013. J Neurosci. 2013. PMID: 23739959 Free PMC article.
The prion protein ligand, stress-inducible phosphoprotein 1, regulates amyloid-β oligomer toxicity.
Ostapchenko VG, Beraldo FH, Mohammad AH, Xie YF, Hirata PH, Magalhaes AC, Lamour G, Li H, Maciejewski A, Belrose JC, Teixeira BL, Fahnestock M, Ferreira ST, Cashman NR, Hajj GN, Jackson MF, Choy WY, MacDonald JF, Martins VR, Prado VF, Prado MA. Ostapchenko VG, et al. Among authors: ferreira st. J Neurosci. 2013 Oct 16;33(42):16552-64. doi: 10.1523/JNEUROSCI.3214-13.2013. J Neurosci. 2013. PMID: 24133259 Free PMC article.
Alzheimer's disease-like pathology induced by amyloid-β oligomers in nonhuman primates.
Forny-Germano L, Lyra e Silva NM, Batista AF, Brito-Moreira J, Gralle M, Boehnke SE, Coe BC, Lablans A, Marques SA, Martinez AM, Klein WL, Houzel JC, Ferreira ST, Munoz DP, De Felice FG. Forny-Germano L, et al. Among authors: ferreira st. J Neurosci. 2014 Oct 8;34(41):13629-43. doi: 10.1523/JNEUROSCI.1353-14.2014. J Neurosci. 2014. PMID: 25297091 Free PMC article.
Cross Talk Between Brain Innate Immunity and Serotonin Signaling Underlies Depressive-Like Behavior Induced by Alzheimer's Amyloid-β Oligomers in Mice.
Ledo JH, Azevedo EP, Beckman D, Ribeiro FC, Santos LE, Razolli DS, Kincheski GC, Melo HM, Bellio M, Teixeira AL, Velloso LA, Foguel D, De Felice FG, Ferreira ST. Ledo JH, et al. Among authors: ferreira st. J Neurosci. 2016 Nov 30;36(48):12106-12116. doi: 10.1523/JNEUROSCI.1269-16.2016. J Neurosci. 2016. PMID: 27903721 Free PMC article.
Astrocyte Transforming Growth Factor Beta 1 Protects Synapses against Aβ Oligomers in Alzheimer's Disease Model.
Diniz LP, Tortelli V, Matias I, Morgado J, Bérgamo Araujo AP, Melo HM, Seixas da Silva GS, Alves-Leon SV, de Souza JM, Ferreira ST, De Felice FG, Gomes FCA. Diniz LP, et al. Among authors: ferreira st. J Neurosci. 2017 Jul 12;37(28):6797-6809. doi: 10.1523/JNEUROSCI.3351-16.2017. Epub 2017 Jun 12. J Neurosci. 2017. PMID: 28607171 Free PMC article.
206 results