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Ablation of secreted phosphoprotein-1 in hepatocytes increases fatty acid oxidation and ameliorates alcohol-associated liver disease.
Das S, Subramaniyam N, Alén R, Komakula SSB, Song Z, Ge X, Han H, Desert R, Athavale D, Magdaleno F, Chen W, Barahona I, Lantvit D, Guzman G, Nieto N. Das S, et al. Among authors: guzman g. Alcohol Clin Exp Res (Hoboken). 2024 May;48(5):781-794. doi: 10.1111/acer.15304. Epub 2024 Mar 19. Alcohol Clin Exp Res (Hoboken). 2024. PMID: 38503560
Role of Hepatocyte-Derived Osteopontin in Liver Carcinogenesis.
Desert R, Ge X, Song Z, Han H, Lantvit D, Chen W, Das S, Athavale D, Abraham-Enachescu I, Blajszczak C, Chen Y, Musso O, Guzman G, Hoshida Y, Nieto N. Desert R, et al. Among authors: guzman g. Hepatol Commun. 2022 Apr;6(4):692-709. doi: 10.1002/hep4.1845. Epub 2021 Nov 3. Hepatol Commun. 2022. PMID: 34730871 Free PMC article.
Intestinal Osteopontin Protects From Alcohol-induced Liver Injury by Preserving the Gut Microbiome and the Intestinal Barrier Function.
Das S, Song Z, Han H, Ge X, Desert R, Athavale D, Babu Komakula SS, Magdaleno F, Chen W, Lantvit D, Guzman G, Nieto N. Das S, et al. Among authors: guzman g. Cell Mol Gastroenterol Hepatol. 2022;14(4):813-839. doi: 10.1016/j.jcmgh.2022.06.012. Epub 2022 Jul 8. Cell Mol Gastroenterol Hepatol. 2022. PMID: 35811073 Free PMC article.
Macrophage-derived Osteopontin (SPP1) Protects From Nonalcoholic Steatohepatitis.
Han H, Ge X, Komakula SSB, Desert R, Das S, Song Z, Chen W, Athavale D, Gaskell H, Lantvit D, Guzman G, Nieto N. Han H, et al. Among authors: guzman g. Gastroenterology. 2023 Jul;165(1):201-217. doi: 10.1053/j.gastro.2023.03.228. Epub 2023 Apr 5. Gastroenterology. 2023. PMID: 37028770 Free PMC article.
Hepatocyte-Specific Loss of PPARγ Protects Mice From NASH and Increases the Therapeutic Effects of Rosiglitazone in the Liver.
Lee SM, Pusec CM, Norris GH, De Jesus A, Diaz-Ruiz A, Muratalla J, Sarmento-Cabral A, Guzman G, Layden BT, Cordoba-Chacon J. Lee SM, et al. Among authors: guzman g. Cell Mol Gastroenterol Hepatol. 2021;11(5):1291-1311. doi: 10.1016/j.jcmgh.2021.01.003. Epub 2021 Jan 11. Cell Mol Gastroenterol Hepatol. 2021. PMID: 33444819 Free PMC article.
416 results