Hajduk PJ - Search Results

1

NMR-driven discovery of benzoylanthranilic acid inhibitors of far upstream element binding protein binding to the human oncogene c-myc promoter.

Huth JR, Yu L, Collins I, Mack J, Mendoza R, Isaac B, Braddock DT, Muchmore SW, Comess KM, Fesik SW, Clore GM, Levens D, Hajduk PJ. Huth JR, et al. Among authors: hajduk pj. J Med Chem. 2004 Sep 23;47(20):4851-7. doi: 10.1021/jm0497803. J Med Chem. 2004. PMID: 15369388

2

Crystallography, NMR and virtual screening: integrated tools for drug discovery.

Muchmore SW, Hajduk PJ. Muchmore SW, et al. Among authors: hajduk pj. Curr Opin Drug Discov Devel. 2003 Jul;6(4):544-9. Curr Opin Drug Discov Devel. 2003. PMID: 12951817 Review.

3

Druggability indices for protein targets derived from NMR-based screening data.

Hajduk PJ, Huth JR, Fesik SW. Hajduk PJ, et al. J Med Chem. 2005 Apr 7;48(7):2518-25. doi: 10.1021/jm049131r. J Med Chem. 2005. PMID: 15801841

4

Discovery of a potent inhibitor of the antiapoptotic protein Bcl-xL from NMR and parallel synthesis.

Petros AM, Dinges J, Augeri DJ, Baumeister SA, Betebenner DA, Bures MG, Elmore SW, Hajduk PJ, Joseph MK, Landis SK, Nettesheim DG, Rosenberg SH, Shen W, Thomas S, Wang X, Zanze I, Zhang H, Fesik SW. Petros AM, et al. Among authors: hajduk pj. J Med Chem. 2006 Jan 26;49(2):656-63. doi: 10.1021/jm0507532. J Med Chem. 2006. PMID: 16420051

5

Discovery of a novel small molecule binding site of human survivin.

Wendt MD, Sun C, Kunzer A, Sauer D, Sarris K, Hoff E, Yu L, Nettesheim DG, Chen J, Jin S, Comess KM, Fan Y, Anderson SN, Isaac B, Olejniczak ET, Hajduk PJ, Rosenberg SH, Elmore SW. Wendt MD, et al. Among authors: hajduk pj. Bioorg Med Chem Lett. 2007 Jun 1;17(11):3122-9. doi: 10.1016/j.bmcl.2007.03.042. Epub 2007 Mar 16. Bioorg Med Chem Lett. 2007. PMID: 17391963

6

Cheminformatic tools for medicinal chemists.

Muchmore SW, Edmunds JJ, Stewart KD, Hajduk PJ. Muchmore SW, et al. Among authors: hajduk pj. J Med Chem. 2010 Jul 8;53(13):4830-41. doi: 10.1021/jm100164z. J Med Chem. 2010. PMID: 20329801 No abstract available.

7

Discovery of a potent and selective Bcl-2 inhibitor using SAR by NMR.

Petros AM, Huth JR, Oost T, Park CM, Ding H, Wang X, Zhang H, Nimmer P, Mendoza R, Sun C, Mack J, Walter K, Dorwin S, Gramling E, Ladror U, Rosenberg SH, Elmore SW, Fesik SW, Hajduk PJ. Petros AM, et al. Among authors: hajduk pj. Bioorg Med Chem Lett. 2010 Nov 15;20(22):6587-91. doi: 10.1016/j.bmcl.2010.09.033. Epub 2010 Sep 15. Bioorg Med Chem Lett. 2010. PMID: 20870405

8

A unified, probabilistic framework for structure- and ligand-based virtual screening.

Swann SL, Brown SP, Muchmore SW, Patel H, Merta P, Locklear J, Hajduk PJ. Swann SL, et al. Among authors: hajduk pj. J Med Chem. 2011 Mar 10;54(5):1223-32. doi: 10.1021/jm1013677. Epub 2011 Feb 10. J Med Chem. 2011. PMID: 21309579

9

NMR-based modification of matrix metalloproteinase inhibitors with improved bioavailability.

Hajduk PJ, Shuker SB, Nettesheim DG, Craig R, Augeri DJ, Betebenner D, Albert DH, Guo Y, Meadows RP, Xu L, Michaelides M, Davidsen SK, Fesik SW. Hajduk PJ, et al. J Med Chem. 2002 Dec 19;45(26):5628-39. doi: 10.1021/jm020160g. J Med Chem. 2002. PMID: 12477346

10

NMR-based discovery of lead inhibitors that block DNA binding of the human papillomavirus E2 protein.

Hajduk PJ, Dinges J, Miknis GF, Merlock M, Middleton T, Kempf DJ, Egan DA, Walter KA, Robins TS, Shuker SB, Holzman TF, Fesik SW. Hajduk PJ, et al. J Med Chem. 1997 Sep 26;40(20):3144-50. doi: 10.1021/jm9703404. J Med Chem. 1997. PMID: 9379433

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

89 results

Search Page