Hall J - Search Results

1

Pharmacodynamic and Pharmacokinetic Properties of Full Phosphorothioate Small Interfering RNAs for Gene Silencing In Vivo.

Berk C, Civenni G, Wang Y, Steuer C, Catapano CV, Hall J. Berk C, et al. Among authors: hall j. Nucleic Acid Ther. 2021 Jun;31(3):237-244. doi: 10.1089/nat.2020.0852. Epub 2020 Apr 20. Nucleic Acid Ther. 2021. PMID: 32311310 Free PMC article.

2

Properties of N(4)-methylated cytidines in miRNA mimics.

Guennewig B, Stoltz M, Menzi M, Dogar AM, Hall J. Guennewig B, et al. Among authors: hall j. Nucleic Acid Ther. 2012 Apr;22(2):109-16. doi: 10.1089/nat.2011.0329. Epub 2012 Feb 28. Nucleic Acid Ther. 2012. PMID: 22373008

3

Multiple microRNAs derived from chemically synthesized precursors regulate thrombospondin 1 expression.

Dogar AM, Semplicio G, Guennewig B, Hall J. Dogar AM, et al. Among authors: hall j. Nucleic Acid Ther. 2014 Apr;24(2):149-59. doi: 10.1089/nat.2013.0467. Epub 2014 Jan 20. Nucleic Acid Ther. 2014. PMID: 24444023 Free PMC article.

4

Short loop-targeting oligoribonucleotides antagonize Lin28 and enable pre-let-7 processing and suppression of cell growth in let-7-deficient cancer cells.

Roos M, Rebhan MA, Lucic M, Pavlicek D, Pradere U, Towbin H, Civenni G, Catapano CV, Hall J. Roos M, et al. Among authors: hall j. Nucleic Acids Res. 2015 Jan;43(2):e9. doi: 10.1093/nar/gku1090. Epub 2014 Nov 6. Nucleic Acids Res. 2015. PMID: 25378324 Free PMC article.

5

Stereochemical bias introduced during RNA synthesis modulates the activity of phosphorothioate siRNAs.

Jahns H, Roos M, Imig J, Baumann F, Wang Y, Gilmour R, Hall J. Jahns H, et al. Among authors: hall j. Nat Commun. 2015 Mar 6;6:6317. doi: 10.1038/ncomms7317. Nat Commun. 2015. PMID: 25744034 Free PMC article.

6

Polyamine-oligonucleotide conjugates: a promising direction for nucleic acid tools and therapeutics.

Menzi M, Lightfoot HL, Hall J. Menzi M, et al. Among authors: hall j. Future Med Chem. 2015;7(13):1733-49. doi: 10.4155/fmc.15.90. Epub 2015 Oct 1. Future Med Chem. 2015. PMID: 26424049 Review.

7

Site-specific conjugation of drug-like fragments to an antimiR scaffold as a strategy to target miRNAs inside RISC.

Brunschweiger A, Gebert LF, Lucic M, Pradère U, Jahns H, Berk C, Hunziker J, Hall J. Brunschweiger A, et al. Among authors: hall j. Chem Commun (Camb). 2016 Jan 4;52(1):156-9. doi: 10.1039/c5cc07478a. Chem Commun (Camb). 2016. PMID: 26505838

8

Properties of short double-stranded RNAs carrying randomized base pairs: toward better controls for RNAi experiments.

Zagalak JA, Menzi M, Schmich F, Jahns H, Dogar AM, Wullschleger F, Towbin H, Hall J. Zagalak JA, et al. Among authors: hall j. RNA. 2015 Dec;21(12):2132-42. doi: 10.1261/rna.053637.115. Epub 2015 Oct 29. RNA. 2015. PMID: 26516083 Free PMC article.

9

Activation of the Lin28/let-7 Axis by Loss of ESE3/EHF Promotes a Tumorigenic and Stem-like Phenotype in Prostate Cancer.

Albino D, Civenni G, Dallavalle C, Roos M, Jahns H, Curti L, Rossi S, Pinton S, D'Ambrosio G, Sessa F, Hall J, Catapano CV, Carbone GM. Albino D, et al. Among authors: hall j. Cancer Res. 2016 Jun 15;76(12):3629-43. doi: 10.1158/0008-5472.CAN-15-2665. Epub 2016 May 2. Cancer Res. 2016. PMID: 27197175

10

A Small-Molecule Inhibitor of Lin28.

Roos M, Pradère U, Ngondo RP, Behera A, Allegrini S, Civenni G, Zagalak JA, Marchand JR, Menzi M, Towbin H, Scheuermann J, Neri D, Caflisch A, Catapano CV, Ciaudo C, Hall J. Roos M, et al. Among authors: hall j. ACS Chem Biol. 2016 Oct 21;11(10):2773-2781. doi: 10.1021/acschembio.6b00232. Epub 2016 Aug 22. ACS Chem Biol. 2016. PMID: 27548809

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