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CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing's sarcoma.
Ross NT, Lohmann F, Carbonneau S, Fazal A, Weihofen WA, Gleim S, Salcius M, Sigoillot F, Henault M, Carl SH, Rodríguez-Molina JB, Miller HR, Brittain SM, Murphy J, Zambrowski M, Boynton G, Wang Y, Chen A, Molind GJ, Wilbertz JH, Artus-Revel CG, Jia M, Akinjiyan FA, Turner J, Knehr J, Carbone W, Schuierer S, Reece-Hoyes JS, Xie K, Saran C, Williams ET, Roma G, Spencer M, Jenkins J, George EL, Thomas JR, Michaud G, Schirle M, Tallarico J, Passmore LA, Chao JA, Beckwith REJ. Ross NT, et al. Among authors: henault m. Nat Chem Biol. 2020 Jan;16(1):50-59. doi: 10.1038/s41589-019-0424-1. Epub 2019 Dec 9. Nat Chem Biol. 2020. PMID: 31819276 Free PMC article.
Author Correction: CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing's sarcoma.
Ross NT, Lohmann F, Carbonneau S, Fazal A, Weihofen WA, Gleim S, Salcius M, Sigoillot F, Henault M, Carl SH, Rodríguez-Molina JB, Miller HR, Brittain SM, Murphy J, Zambrowski M, Boynton G, Wang Y, Chen A, Molind GJ, Wilbertz JH, Artus-Revel CG, Jia M, Akinjiyan FA, Turner J, Knehr J, Carbone W, Schuierer S, Reece-Hoyes JS, Xie K, Saran C, Williams ET, Roma G, Spencer M, Jenkins J, George EL, Thomas JR, Michaud G, Schirle M, Tallarico J, Passmore LA, Chao JA, Beckwith REJ. Ross NT, et al. Among authors: henault m. Nat Chem Biol. 2020 Apr;16(4):479. doi: 10.1038/s41589-020-0508-y. Nat Chem Biol. 2020. PMID: 32139909
An IMiD-inducible degron provides reversible regulation for chimeric antigen receptor expression and activity.
Carbonneau S, Sharma S, Peng L, Rajan V, Hainzl D, Henault M, Yang C, Hale J, Shulok J, Tallarico J, Porter J, Brogdon JL, Dranoff G, Bradner JE, Hild M, Guimaraes CP. Carbonneau S, et al. Among authors: henault m. Cell Chem Biol. 2021 Jun 17;28(6):802-812.e6. doi: 10.1016/j.chembiol.2020.11.012. Epub 2020 Dec 16. Cell Chem Biol. 2021. PMID: 33333026 Free article.
DRUG-seq Provides Unbiased Biological Activity Readouts for Neuroscience Drug Discovery.
Li J, Ho DJ, Henault M, Yang C, Neri M, Ge R, Renner S, Mansur L, Lindeman A, Kelly B, Tumkaya T, Ke X, Soler-Llavina G, Shanker G, Russ C, Hild M, Gubser Keller C, Jenkins JL, Worringer KA, Sigoillot FD, Ihry RJ. Li J, et al. Among authors: henault m. ACS Chem Biol. 2022 Jun 17;17(6):1401-1414. doi: 10.1021/acschembio.1c00920. Epub 2022 May 4. ACS Chem Biol. 2022. PMID: 35508359 Free PMC article.
Englerin A Agonizes the TRPC4/C5 Cation Channels to Inhibit Tumor Cell Line Proliferation.
Carson C, Raman P, Tullai J, Xu L, Henault M, Thomas E, Yeola S, Lao J, McPate M, Verkuyl JM, Marsh G, Sarber J, Amaral A, Bailey S, Lubicka D, Pham H, Miranda N, Ding J, Tang HM, Ju H, Tranter P, Ji N, Krastel P, Jain RK, Schumacher AM, Loureiro JJ, George E, Berellini G, Ross NT, Bushell SM, Erdemli G, Solomon JM. Carson C, et al. Among authors: henault m. PLoS One. 2015 Jun 22;10(6):e0127498. doi: 10.1371/journal.pone.0127498. eCollection 2015. PLoS One. 2015. PMID: 26098886 Free PMC article.
An IMiD-inducible degron provides reversible regulation for chimeric antigen receptor expression and activity.
Carbonneau S, Sharma S, Peng L, Rajan V, Hainzl D, Henault M, Yang C, Hale J, Shulok J, Tallarico J, Porter J, Brogdon JL, Dranoff G, Bradner JE, Hild M, Guimaraes CP. Carbonneau S, et al. Among authors: henault m. Cell Chem Biol. 2021 Apr 15;28(4):583. doi: 10.1016/j.chembiol.2021.02.003. Cell Chem Biol. 2021. PMID: 33861956 Free article. No abstract available.
DRUG-seq for miniaturized high-throughput transcriptome profiling in drug discovery.
Ye C, Ho DJ, Neri M, Yang C, Kulkarni T, Randhawa R, Henault M, Mostacci N, Farmer P, Renner S, Ihry R, Mansur L, Keller CG, McAllister G, Hild M, Jenkins J, Kaykas A. Ye C, et al. Among authors: henault m. Nat Commun. 2018 Oct 17;9(1):4307. doi: 10.1038/s41467-018-06500-x. Nat Commun. 2018. PMID: 30333485 Free PMC article.
61 results